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Synuclein beta
mammalian protein found in Homo sapiens
beta-synuclein
I(2)-synuclein
SNCB
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q16143
part of
Beta-synuclein
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q16143
Synuclein
1 reference
Transporter Classification Database ID
1.C.77.1.2
retrieved
2 October 2019
based on heuristic
hierarchical database ID heuristic
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q16143
encoded by
SNCB
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q16143
molecular function
phospholipase inhibitor activity
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Genomic organization and expression of the human beta-synuclein gene (SNCB)
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
TAS
calcium ion binding
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
GOA
curator
UniProt
UniProt protein ID
Q16143
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
IDA
transition metal ion binding
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Differences in the binding of copper(I) to α- and β-synuclein
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
IMP
cuprous ion binding
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Differences in the binding of copper(I) to α- and β-synuclein
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
IMP
cell component
inclusion body
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Relationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
IDA
synapse
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
IEA
cytoplasm
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q16143
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
IEA
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
TAS
presynapse
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
IEA
biological process
negative regulation of neuron apoptotic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
IEA
synapse organization
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
IEA
dopamine metabolic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
IEA
chemical synaptic transmission
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
IEA
negative regulation of catalytic activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
IEA
response to metal ion
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
TAS
synaptic vesicle endocytosis
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16143
determination method
IEA
Gene Atlas image
PBB GE SNCB 207853 s at fs.png
732 × 530; 11 KB
0 references
exact match
http://purl.uniprot.org/uniprot/Q16143
1 reference
stated in
Identifiers.org
Identifiers
MeSH descriptor ID
D051846
0 references
RefSeq protein ID
NP_001001502
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6620
NP_001304963
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6620
NP_001304964
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6620
NP_001304965
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6620
NP_001304966
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6620
NP_003076
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6620
XP_006714977
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6620
XP_006714978
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6620
XP_006714979
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6620
XP_011532942
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6620
NP_001350069
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6620
UniProt protein ID
Q16143
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q16143
Ensembl protein ID
ENSP00000308057
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000308057
ENSP00000377296
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000377296
ENSP00000422223
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000422223
ENSP00000424073
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000424073
ENSP00000479489
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000479489
Transporter Classification Database ID
1.C.77.1.2
2 references
stated in
Transporter Classification database
retrieved
13 March 2020
stated in
Transporter Classification database
retrieved
29 April 2020
UMLS CUI
C0245467
1 reference
based on heuristic
inferred by common MeSH mappings on source and on Wikidata
stated in
UMLS 2023
retrieved
25 May 2023
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