(Q87981906)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29511104%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

Metabolic shift from glycogen to trehalose promotes lifespan and healthspan in Caenorhabditis elegans (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29511104%20AND%20SRC:MED&resulttype=core&format=json

glycogen metabolic process

19 March 2020

main subject

Caenorhabditis elegans

1 reference

1 reference

1 reference

1 reference

5

Heidi A Tissenbaum

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29511104%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

author name string

Yonghak Seo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29511104%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Samuel Kingsley

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29511104%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Griffin Walker

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29511104%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Michelle A Mondoux

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29511104%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

publication date

6 March 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29511104%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

19 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29511104%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

volume

115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29511104%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29511104%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

page(s)

E2791-E2800

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29511104%20AND%20SRC:MED&resulttype=core&format=json

The role of trehalose in the physiology of nematodes

19 March 2020

cites work

1 reference

12 December 2020

Specific features of glycogen metabolism in the liver

1 reference

12 December 2020

Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling

1 reference

12 December 2020

Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway

1 reference

12 December 2020

daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans

1 reference

12 December 2020

Trehalose: a review of properties, history of use and human tolerance, and results of multiple safety studies

1 reference

12 December 2020

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

1 reference

12 December 2020

New insights on trehalose: a multifunctional molecule

1 reference

12 December 2020

DAF-16 target genes that control C. elegans life-span and metabolism.

1 reference

12 December 2020

Control of glycogen deposition.

1 reference

12 December 2020

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

1 reference

12 December 2020

Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16.

1 reference

12 December 2020

Autophagy genes are essential for dauer development and life-span extension in C. elegans

1 reference

12 December 2020

Glucose-6-phosphatase of the liver in glycogen storage disease

1 reference

12 December 2020

Claude Bernard and the discovery of glycogen; a century of retrospect.

1 reference

12 December 2020

Trehalose metabolism genes in Caenorhabditis elegans and filarial nematodes

1 reference

12 December 2020

Liver glycogen disease (von Gierke's disease)

1 reference

12 December 2020

Glyoxalase I--structure, function and a critical role in the enzymatic defence against glycation

1 reference

12 December 2020

Fructose-mediated non-enzymatic glycation: sweet coupling or bad modification

1 reference

12 December 2020

A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout

1 reference

12 December 2020

Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation

1 reference

12 December 2020

Targets of DAF-16 involved in Caenorhabditis elegans adult longevity and dauer formation.

1 reference

12 December 2020

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

1 reference

12 December 2020

Autophagy regulates ageing in C. elegans.

1 reference

12 December 2020

PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans

1 reference

12 December 2020

Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress

1 reference

12 December 2020

Maintenance of C. elegans

1 reference

12 December 2020

Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans.

1 reference

12 December 2020

A role for autophagy in the extension of lifespan by dietary restriction in C. elegans

1 reference

12 December 2020

Mutations in the glucose-6-phosphatase-alpha (G6PC) gene that cause type Ia glycogen storage disease

1 reference

12 December 2020

Intermediary metabolism

1 reference

12 December 2020

Adaptive sugar provisioning controls survival of C. elegans embryos in adverse environments

1 reference

12 December 2020

C. elegans as model for the study of high glucose- mediated life span reduction

1 reference

12 December 2020

Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression

1 reference

12 December 2020

Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol

1 reference

12 December 2020

Trehalose extends longevity in the nematode Caenorhabditis elegans

1 reference

12 December 2020

A new DAF-16 isoform regulates longevity.

1 reference

12 December 2020

DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO

1 reference

12 December 2020

The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing

1 reference

12 December 2020

O-linked-N-acetylglucosamine cycling and insulin signaling are required for the glucose stress response in Caenorhabditis elegans

1 reference

12 December 2020

High glucose diets shorten lifespan of Caenorhabditis elegans via ectopic apoptosis induction

1 reference

12 December 2020

Trehalose renders the dauer larva of Caenorhabditis elegans resistant to extreme desiccation

1 reference

12 December 2020

Glycogen and its metabolism: some new developments and old themes

1 reference

12 December 2020

Paternal dietary restriction affects progeny fat content in Caenorhabditis elegans

1 reference

12 December 2020

Lessons from C. elegans: signaling pathways for longevity

1 reference

12 December 2020

A review of chemical composition and nutritional value of wild-growing and cultivated mushrooms

1 reference

12 December 2020

Energy and fructose from beverages sweetened with sugar or high-fructose corn syrup pose a health risk for some people

1 reference

12 December 2020

The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans

1 reference

12 December 2020

Life-long spontaneous exercise does not prolong lifespan but improves health span in mice.

1 reference

12 December 2020

Added sugar intake and cardiovascular diseases mortality among US adults

1 reference

12 December 2020

Dietary sugar and body weight: have we reached a crisis in the epidemic of obesity and diabetes?: health be damned! Pour on the sugar

1 reference

12 December 2020

Glucose feeding during development aggravates the toxicity of the organophosphorus insecticide Monocrotophos in the nematode, Caenorhabditis elegans.

1 reference

12 December 2020

Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan.

1 reference

12 December 2020

Pompe disease: literature review and case series

1 reference

12 December 2020

DAF-16 target identification in C. elegans: past, present and future

1 reference

12 December 2020

daf-16/FOXO and glod-4/glyoxalase-1 are required for the life-prolonging effect of human insulin under high glucose conditions in Caenorhabditis elegans

1 reference

12 December 2020

Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

1 reference

12 December 2020

mir-233 modulates the unfolded protein response in C. elegans during Pseudomonas aeruginosa infection

1 reference

12 December 2020

Glucose induces sensitivity to oxygen deprivation and modulates insulin/IGF-1 signaling and lipid biosynthesis in Caenorhabditis elegans.

1 reference

12 December 2020

1 reference

12 December 2020

Glycogen Fuels Survival During Hyposmotic-Anoxic Stress in Caenorhabditis elegans

1 reference

12 December 2020

High-glucose diets have sex-specific effects on aging in C. elegans: toxic to hermaphrodites but beneficial to males

1 reference

12 December 2020

Longevity Genes Revealed by Integrative Analysis of Isoform-Specific daf-16/FoxO Mutants of Caenorhabditis elegans

1 reference

12 December 2020

Integration of carbohydrate metabolism and redox state controls dauer larva formation in Caenorhabditis elegans.

1 reference

12 December 2020

FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores

1 reference

12 December 2020

SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fat

1 reference

12 December 2020

Mystery solved: Trehalose kickstarts autophagy by blocking glucose transport

1 reference

12 December 2020

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

1 reference

12 December 2020

Advanced Glycation End-Products and Their Receptors: Related Pathologies, Recent Therapeutic Strategies, and a Potential Model for Future Neurodegeneration Studies

1 reference

12 December 2020

Trehalose, sucrose and raffinose are novel activators of autophagy in human keratinocytes through an mTOR-independent pathway.

1 reference

12 December 2020

Lower Doses of Fructose Extend Lifespan in Caenorhabditis elegans.

1 reference

12 December 2020

A cross-sectional study of male and female C57BL/6Nia mice suggests lifespan and healthspan are not necessarily correlated

1 reference

12 December 2020

SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy.

1 reference

12 December 2020

Glucose-rich diet aggravates monocrotophos-induced dopaminergic neuronal dysfunction in Caenorhabditis elegans.

1 reference

12 December 2020

Daily Intake of Trehalose Is Effective in the Prevention of Lifestyle-Related Diseases in Individuals with Risk Factors for Metabolic Syndrome

1 reference

12 December 2020

High glucose alters tendon homeostasis through downregulation of the AMPK/Egr1 pathway.

1 reference

12 December 2020

A high-glucose diet affects Achilles tendon healing in rats

1 reference

12 December 2020

Dietary Sugars and Endogenous Formation of Advanced Glycation Endproducts: Emerging Mechanisms of Disease

1 reference

12 December 2020

Glycogen controls Caenorhabditis elegans lifespan and resistance to oxidative stress

1 reference

12 December 2020

Trehalose improves traumatic brain injury-induced cognitive impairment

1 reference

12 December 2020

daf-16/FoxO promotes gluconeogenesis and trehalose synthesis during starvation to support survival.

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1714178115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29511104%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29511104%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference