# Changelog
# 2023-02-05 Version 1.1, added some comments
# 2022-12-16 Version 1.0, use only labels in English
# based on https://raw.githubusercontent.com/SuLab/genewikiworld/master/img/update.png
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX wd: <http://www.wikidata.org/entity/>
PREFIX wdt: <http://www.wikidata.org/prop/direct/>
PREFIX : <http://example.org/>
start= @:active_site OR
@:anatomical_structure OR
@:binding_site OR
@:biological_pathway OR
@:biological_process OR
@:cellular_component OR
@:chemical_compound OR
@:chromosome OR
@:disease OR
@:gene OR
@:mechanism_of_action OR
@:medication OR
@:molecular_function OR
@:pharmaceutical_product OR
@:pharmacologic_action OR
@:protein_domain OR
@:protein_family OR
@:protein OR
@:sequence_variant OR
@:supersecondary_structure OR
@:symptom OR
@:taxon OR
@:therapeutic_use
:active_site EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q423026 ] ;
wdt:P361 @:protein_family * ;
wdt:P527 @:protein_family * ;
}
:anatomical_structure EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q4936952 ] ;
wdt:P361 @:anatomical_structure * ; # part of
wdt:P527 @:anatomical_structure * # has part
}
:binding_site EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q616005 ] ;
wdt:P361 @:protein_family *; # part of (P361)
wdt:P527 @:protein_family *; # has part(s) (P527)
}
:biological_pathway EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q4915012 ] ;
wdt:P527 @:biological_pathway * ; # has part(s) (P527)
wdt:P361 @:biological_pathway * ; # part of (P361)
wdt:P361 @:gene * ; # part of (P361)
wdt:P527 @:gene * ; # has part(s) (P527)
wdt:P361 @:medication *; # part of (P361)
wdt:P527 @:medication * ; # has part(s) (P527)
wdt:P361 @:chemical_compound * ; # part of (P361)
wdt:P527 @:chemical_compound * ; # has part(s) (P527)
wdt:P703 @:taxon * ; # found in taxon (P703)
wdt:P1050 @:disease*; # medical condition (P1050)
}
:biological_process EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [wd:Q2996394] ;
wdt:P279 @:biological_process * ; # subclass of (P279)
wdt:P361 @:biological_process * ; # part of (P361)
wdt:P527 @:biological_process * ; # has part(s) (P527)
wdt:P128 @:biological_process * ; # has part(s) (P527)
wdt:P128 @:molecular_function * ; # regulates (molecular biology) (P128)
wdt:P361 @:medication * ; # part of (P361)
wdt:P527 @:medication * ; # has part(s) (P527)
wdt:P361 @:chemical_compound * ; # part of (P361)
wdt:P527 @:chemical_compound * ; # has part(s) (P527)
wdt:P279 @:biological_process * # subclass of (P279)
}
:cellular_component EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [wd:Q5058355];
wdt:P279 @:cellular_component * ; # subclass of (P279)
wdt:P361 @:cellular_component * ; # part of (P361)
wdt:P681 @:cellular_component * ; # cell component (P681)
wdt:P527 @:cellular_component * ; # has part(s) (P527)
}
:chemical_compound EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q11173 ] ;
wdt:P3364 @:chemical_compound * ;
wdt:P769 @:chemical_compound * ;
wdt:P2868 @:pharmacologic_action * ;
wdt:P769 @:pharmacologic_action * ; # significant drug interaction (P769)
wdt:P279 @:pharmacologic_action * ; # subclass of (P279)
wdt:P361 @:medication * ; # part of (P361)
wdt:P527 @:medication * ; # has part(s) (P527)
wdt:P2868 @:mechanism_of_action *; # subject has role (P2868)
wdt:P3489 @:disease * ; # pregnancy category (P3489)
}
:chromosome EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q37748 ] ;
}
:disease EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q12136 ] ;
wdt:P279 @:disease * ;
wdt:P780 @:disease * ; # symptoms and signs (P780)
wdt:P828 @:taxon * ; # has cause (P828)
wdt:P2293 @:gene * ; # genetic association (P2293)
wdt:P927 @:anatomical_structure * ; # anatomical location (P927)
wdt:P2176 @:medication * ; # drug or therapy used for treatment (P2176)
wdt:P2176 @:chemical_compound * ; # drug or therapy used for treatment (P2176)
wdt:P2176 @:therapeutic_use * ; # drug or therapy used for treatment (P2176)
wdt:P2175 @:medication * ; # medical condition treated (P2175)
wdt:P2175 @:chemical_compound * ; # medical condition treated (P2175)
wdt:P2175 @:therapeutic_use * ; # medical condition treated (P2175)
}
:gene EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q7187 ] ;
wdt:P684 @:gene * ; # ortholog (P684)
wdt:P2293 @:disease *; # genetic association (P2293)
wdt:P703 @:taxon * ; # found in taxon (P703)
wdt:P1057 @:chromosome * ; # chromosome (P1057)
wdt:P682 @:biological_process * ; # biological process (P682)
wdt:P688 @:protein * ; # encodes (P688)
}
:mechanism_of_action EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q3271540 ] ;
}
:medication EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q12140 ] ;
wdt:P2175 @:disease * ; # medical condition treated (P2175)
wdt:P3780 @:pharmaceutical_product * ; # active ingredient in (P3780)
wdt:P769 @:pharmacologic_action * ; # significant drug interaction (P769)
wdt:P769 @:chemical_compound * ; # significant drug interaction (P769)
wdt:P769 @:therapeutic_use * ; # significant drug interaction (P769)
wdt:P2868 @:pharmacologic_action * ; # subject has role (P2868)
wdt:P2868 @:therapeutic_use * ; # subject has role (P2868)
wdt:P279 @:pharmacologic_action * ; # subclass of (P279)
wdt:P279 @:therapeutic_use * ; # subclass of (P279)
wdt:P2868 @:mechanism_of_action * ; # subject has role (P2868)
wdt:P2175 @:symptom * # medical condition treated (P2175)
}
:molecular_function EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q14860489 ] ;
wdt:P361 @:molecular_function *;
wdt:P527 @:molecular_function *;
wdt:P279 @:molecular_function *;
}
:pharmaceutical_product EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q28885102 ] ;
wdt:P3781 @:therapeutic_use * ; # has active ingredient (P3781)
wdt:P3781 @:pharmacologic_action * ; # has active ingredient (P3781)
wdt:P3781 @:chemical_compound * ; # has active ingredient (P3781)
wdt:P3781 @:medication * ; # has active ingredient (P3781)
wdt:P3780 @:therapeutic_use * ; # active ingredient in (P3780)
wdt:P3780 @:pharmacologic_action * ; # active ingredient in (P3780)
wdt:P3780 @:chemical_compound * ; # active ingredient in (P3780)
wdt:P3780 @:medication * ; # active ingredient in (P3780)
wdt:P4044 @:disease *; # therapeutic area (P4044)
}
:pharmacologic_action EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [wd:Q50377224 ] ;
wdt:P3780 @:pharmaceutical_product * ; # active ingredient in (P3780)
wdt:P3781 @:pharmaceutical_product * ; # has active ingredient (P3781)
wdt:P2175 @:disease * ; # medical condition treated (P2175)
wdt:P2176 @:disease * ; # drug or therapy used for treatment (P2176)
}
:protein_domain EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q898273 ] ;
wdt:P279 @:protein_domain * ; # subclass of (P279)
wdt:P128 @:protein_domain * ; # regulates (molecular biology) (P128)
wdt:P527 @:protein_domain * ; # has part(s) (P527)
wdt:P361 @:protein_domain * ; # part of (P361)
}
:protein_family EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q417841 ] ;
wdt:P527 @:protein * ; # has part(s) (P527)
wdt:P279 @:protein_family* ; # subclass of (P279)
wdt:P527 @:protein * ; # part of (P361)
}
:protein EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q8054 ] ;
wdt:P129 @:protein * ; # physically interacts with (P129)
wdt:P681 @:protein * ; # cell component (P681)
wdt:P129 @:medication * ; # physically interacts with (P129)
wdt:P680 @:molecular_function * ; # molecular function (P680)
wdt:P681 @:cellular_component * ; # cell component (P681)
wdt:P681 @:anatomical_structure * ; # cell component (P681)
wdt:P682 @:biological_process * ; # biological process (P682)
wdt:P527 @:active_site * ; # has part(s) (P527)
wdt:P361 @:active_site * ; # part of (P361)
wdt:P527 @:protein_domain * ; # has part(s) (P527)
wdt:P361 @:protein_domain * ; # part of (P361)
wdt:P361 @:protein_family * ; # part of (P361)
wdt:P527 @:protein_family * ; # has part(s) (P527)
wdt:P527 @:active_site * ;
wdt:P361 @:active_site * ;
wdt:P361 @:binding_site * ;
wdt:P527 @:binding_site * ;
wdt:P129 @:chemical_compound * ; # physically interacts with (P129)
wdt:P129 @:medication * ; # physically interacts with (P129)
wdt:P702 @:gene * ; # encoded by (P702)
wdt:P703 @:taxon * ; # found in taxon (P703)
}
:sequence_variant EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q15304597 ] ;
wdt:P3433 @:gene * ; # sequence variant (Q15304597)
wdt:P3355 @:chemical_compound * ; # negative therapeutic predictor for (P3355)
wdt:P3354 @:chemical_compound * ; # positive therapeutic predictor for (P3354)
wdt:P3354 @:medication * ;
wdt:P3355 @:medication * ;
wdt:P1057 @:chromosome * ; # chromosome (P1057)
}
:supersecondary_structure EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q7644128 ] ;
wdt:P361 @:protein *;
wdt:P361 @:protein_family *;
wdt:P361 @:protein_domain * ;
}
:symptom EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q169872 ];
wdt:P2176 @:chemical_compound *; # drug or therapy used for treatment (P2176)
}
:taxon EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q16521 ] ;
}
:therapeutic_use EXTRA wdt:P31 {
rdfs:label [ @en ] ;
wdt:P31 [ wd:Q50379781 ] ;
}
