Property talk:P1918

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altered regulation leads to
this property should link a gene and a disease due to altered regulation

Data type	Item
Domain	According to this template: subclasses of gene (Q7187) According to statements in the property: gene (Q7187) When possible, data should only be stored as statements
Allowed values	Wikidata Item ID (Q*) with subclass disease (Q12136) (note: this should be moved to the property statements)
Example	SNCA (Q14862268) → Parkinson's disease (Q11085)
Source	Clinvar, Pubmed (note: this information should be moved to a property statement; use property source website for the property (P1896))
Robot and gadget jobs	Robots will add this property to the appropriate WD items.
Lists	Items with the most statements of this property Count of items by number of statements (chart) Items with the most statements Items with the fewest statements Count of items by number of sitelinks (chart) Items with the most sitelinks Items with the most sitelinks, but no link to one Wikipedia (sample: Welsh Wikipedia, cywiki) Items with the fewest sitelinks Most linked wikis Items with the most identifier properties By value of property Most statements Fewest statements Most sitelinks Most linked wikis Total of sitelinks on items Most identifiers Fewest identifiers Items with no other statements Most recently created items Items with novalue claims Items with unknown value claims Usage history (total) Usage history (main statement) Database reports/Constraint violations/P1918 Map Random list
Proposal discussion	Proposal discussion
Current uses	Total 15 Main statement 14 93.3% of uses Qualifier 1 6.7% of uses
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[create Create a translatable help page (preferably in English) for this property to be included here]

Type “gene (Q7187)”: item must contain property “instance of (P31), subclass of (P279)” with classes “gene (Q7187)” or their subclasses (defined using subclass of (P279)). (Help)

Exceptions are possible as rare values may exist. Exceptions can be specified using exception to constraint (P2303).
List of violations of this constraint: Database reports/Constraint violations/P1918#Type Q7187, SPARQL

Value type “disease (Q12136)”: This property should use items as value that contain property “subclass of (P279)”. On these, the value for subclass of (P279) should be an item that uses subclass of (P279) with value disease (Q12136) (or a subclass thereof). (Help)

Exceptions are possible as rare values may exist. Exceptions can be specified using exception to constraint (P2303).
List of violations of this constraint: Database reports/Constraint violations/P1918#Value type Q12136, SPARQL

Scope is as main value (Q54828448): the property must be used by specified way only (Help)

List of violations of this constraint: Database reports/Constraint violations/P1918#Scope, hourly updated report, SPARQL

Can the type constraint be expanded to proteins?

If not, what would be the best way to model/link alterations in protein regulation to a disease? P1917 (posttranslational modification associated with disease) could probably be used for regulatory mechanics involving PTMS, but protein activity can be allosterically regulated as well. -- Gtsulab (talk) 21:35, 31 July 2019 (UTC)