(Q1263065)

insulin-like growth factor I

1 reference

stated in

Insulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Insulin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

3 references

8 April 2019

Hypothalamic/pituitary-axis of the spontaneous dwarf rat: autofeedback regulation of growth hormone (GH) includes suppression of GH releasing-hormone receptor messenger ribonucleic acid

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Purification of somatomedin-C from human plasma: chemical and biological properties, partial sequence analysis, and relationship to other somatomedins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity

insulin receptor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

2 references

8 April 2019

Cross-talk between integrin α6β4 and insulin-like growth factor-1 receptor (IGF1R) through direct α6β4 binding to IGF1 and subsequent α6β4-IGF1-IGF1R ternary complex formation in anchorage-independent conditions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

7 references

8 April 2019

Fine details of IGF-1R activation, inhibition, and asymmetry determined by associated hydrogen /deuterium-exchange and peptide mass mapping

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Structural and functional analysis of HtrA1 and its subdomains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Structural basis for the regulation of insulin-like growth factors by IGF binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Substitutions for hydrophobic amino acids in the N-terminal domains of IGFBP-3 and -5 markedly reduce IGF-I binding and alter their biologic actions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

insulin-like growth factor receptor binding

IPI

4 references

8 April 2019

Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Both type I and II insulin-like growth factor receptor binding increase during lactogenesis in bovine mammary tissue

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Stimulation of DNA synthesis in chicken muscle satellite cells by insulin and insulin-like growth factors: evidence for exclusive mediation by a type-I insulin-like growth factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

The human plasma proteome: a nonredundant list developed by combination of four separate sources

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

insulin-like growth factor binding protein complex

ISS

1 reference

8 April 2019

Substitutions for hydrophobic amino acids in the N-terminal domains of IGFBP-3 and -5 markedly reduce IGF-I binding and alter their biologic actions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

platelet alpha granule lumen

IC

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

insulin-like growth factor ternary complex

1 reference

8 April 2019

Insulin-like growth factor (IGF)-binding protein 5 forms an alternative ternary complex with IGFs and the acid-labile subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

alphav-beta3 integrin-IGF-1-IGF1R complex

1 reference

8 April 2019

The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05019&geneProductId=UniProtKB:P05019

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Induction of insulin-like growth factor 1 splice forms by subfragments of myofibrillar proteins

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Ethnic disparity in the relationship between obesity and plasma insulin-like growth factors: the multiethnic cohort

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Purification of somatomedin-C from human plasma: chemical and biological properties, partial sequence analysis, and relationship to other somatomedins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Early-age heat exposure affects skeletal muscle satellite cell proliferation and differentiation in chicks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of transcription regulatory region DNA binding

biological process

1 reference

8 April 2019

Concerted regulation of the porcine steroidogenic acute regulatory protein gene promoter activity by follicle-stimulating hormone and insulin-like growth factor I in granulosa cells involves GATA-4 and CCAAT/enhancer binding protein beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

skeletal system development

1 reference

8 April 2019

Skeletal muscle hypertrophy is mediated by a Ca2+-dependent calcineurin signalling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of glucose import

1 reference

8 April 2019

Stimulation of glucose transport in osteoblastic cells by parathyroid hormone and insulin-like growth factor I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

Skeletal muscle hypertrophy is mediated by a Ca2+-dependent calcineurin signalling pathway

muscle organ development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of Ras protein signal transduction

1 reference

8 April 2019

Insulin-like growth factor-I augments erythropoietin-induced proliferation through enhanced tyrosine phosphorylation of STAT5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

1 reference

8 April 2019

Early-age heat exposure affects skeletal muscle satellite cell proliferation and differentiation in chicks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of cardiac muscle hypertrophy

positive regulation of smooth muscle cell migration

1 reference

8 April 2019

Substitutions for hydrophobic amino acids in the N-terminal domains of IGFBP-3 and -5 markedly reduce IGF-I binding and alter their biologic actions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

1 reference

26 September 2017

Substitutions for hydrophobic amino acids in the N-terminal domains of IGFBP-3 and -5 markedly reduce IGF-I binding and alter their biologic actions

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05019&geneProductId=UniProtKB:P05019

positive regulation of insulin-like growth factor receptor signaling pathway

phosphatidylinositol 3-kinase signaling

1 reference

8 April 2019

Insulin-like growth factor I induces proliferation and migration of porcine trophectoderm cells through multiple cell signaling pathways, including protooncogenic protein kinase 1 and mitogen-activated protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of DNA binding

1 reference

8 April 2019

The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

Ras protein signal transduction

1 reference

8 April 2019

Involvement of Ras and Ral in chemotactic migration of skeletal myoblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

cell population proliferation

positive regulation of mitotic nuclear division

positive regulation of trophectodermal cell proliferation

1 reference

8 April 2019

Insulin-like growth factor I induces proliferation and migration of porcine trophectoderm cells through multiple cell signaling pathways, including protooncogenic protein kinase 1 and mitogen-activated protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of glycogen biosynthetic process

1 reference

8 April 2019

Stimulation of glucose transport in osteoblastic cells by parathyroid hormone and insulin-like growth factor I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of fibroblast proliferation

1 reference

8 April 2019

Purification of somatomedin-C from human plasma: chemical and biological properties, partial sequence analysis, and relationship to other somatomedins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

Insulin-like growth factor I induces proliferation and migration of porcine trophectoderm cells through multiple cell signaling pathways, including protooncogenic protein kinase 1 and mitogen-activated protein kinase

ERK1 and ERK2 cascade

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

negative regulation of extrinsic apoptotic signaling pathway

1 reference

8 April 2019

Differential effects of insulin-like growth factor-1 and atheroma-associated cytokines on cell proliferation and apoptosis in plaque smooth muscle cells of symptomatic and asymptomatic patients with carotid stenosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

1 reference

8 April 2019

ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

negative regulation of oocyte development

1 reference

8 April 2019

In vivo oocyte developmental competence is reduced in lean but not in obese superovulated dairy cows after intraovarian administration of IGF1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of transcription, DNA-templated

3 references

8 April 2019

Concerted regulation of the porcine steroidogenic acute regulatory protein gene promoter activity by follicle-stimulating hormone and insulin-like growth factor I in granulosa cells involves GATA-4 and CCAAT/enhancer binding protein beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Insulin-like growth factor-I augments erythropoietin-induced proliferation through enhanced tyrosine phosphorylation of STAT5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

bone mineralization involved in bone maturation

1 reference

8 April 2019

Insulin-like growth factor-I induces early osteoblast gene expression in human mesenchymal stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of MAPK cascade

2 references

1 reference

8 April 2019

The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

proteoglycan biosynthetic process

positive regulation of activated T cell proliferation

1 reference

8 April 2019

Effects of insulin-like growth factors and insulin-like growth factor binding protein-2 on the in vitro proliferation of peripheral blood mononuclear cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of epithelial cell proliferation

1 reference

8 April 2019

Purification of somatomedin-C from human plasma: chemical and biological properties, partial sequence analysis, and relationship to other somatomedins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

negative regulation of release of cytochrome c from mitochondria

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

Regulation of insulin-like growth factor-binding protein-5 by insulin-like growth factor I and interleukin-1alpha in ovine articular chondrocytes

ISS

protein stabilization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

The IGF-I splice variant MGF increases progenitor cells in ALS, dystrophic, and normal muscle

myotube cell development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of DNA replication

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05019&geneProductId=UniProtKB:P05019

26 September 2017

Insulin-like growth factor-I augments erythropoietin-induced proliferation through enhanced tyrosine phosphorylation of STAT5

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05019&geneProductId=UniProtKB:P05019

26 September 2017

Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI 8226

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05019&geneProductId=UniProtKB:P05019

The IGF-I splice variant MGF increases progenitor cells in ALS, dystrophic, and normal muscle

myoblast proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration

1 reference

8 April 2019

The IGF-I splice variant MGF increases progenitor cells in ALS, dystrophic, and normal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of protein secretion

1 reference

8 April 2019

Regulation of insulin-like growth factor-binding protein-5 by insulin-like growth factor I and interleukin-1alpha in ovine articular chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of glycoprotein biosynthetic process

1 reference

8 April 2019

Regulation of insulin-like growth factor-binding protein-5 by insulin-like growth factor I and interleukin-1alpha in ovine articular chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

regulation of gene expression

1 reference

8 April 2019

In vivo oocyte developmental competence is reduced in lean but not in obese superovulated dairy cows after intraovarian administration of IGF1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

phosphatidylinositol-mediated signaling

1 reference

8 April 2019

Distinctive effects of the carboxyl-terminal sequence of the insulin-like growth factor I receptor on its signaling functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of smooth muscle cell proliferation

2 references

8 April 2019

Substitutions for hydrophobic amino acids in the N-terminal domains of IGFBP-3 and -5 markedly reduce IGF-I binding and alter their biologic actions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Differential effects of insulin-like growth factor-1 and atheroma-associated cytokines on cell proliferation and apoptosis in plaque smooth muscle cells of symptomatic and asymptomatic patients with carotid stenosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

1 reference

8 April 2019

Insulin-like growth factor (IGF-I) induces myotube hypertrophy associated with an increase in anaerobic glycolysis in a clonal skeletal-muscle cell model

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

protein kinase B signaling

1 reference

8 April 2019

Insulin-like growth factor I induces proliferation and migration of porcine trophectoderm cells through multiple cell signaling pathways, including protooncogenic protein kinase 1 and mitogen-activated protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

regulation of multicellular organism growth

1 reference

8 April 2019

Congenital gigantism due to growth hormone-releasing hormone excess and pituitary hyperplasia with adenomatous transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of cell migration

IEP

1 reference

8 April 2019

Insulin-like growth factor I induces proliferation and migration of porcine trophectoderm cells through multiple cell signaling pathways, including protooncogenic protein kinase 1 and mitogen-activated protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

platelet degranulation

1 reference

8 April 2019

positive regulation of calcineurin-NFAT signaling cascade

1 reference

8 April 2019

The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of phosphatidylinositol 3-kinase signaling

1 reference

8 April 2019

Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI 8226

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

The IGF-I splice variant MGF increases progenitor cells in ALS, dystrophic, and normal muscle

myoblast differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

glycolate metabolic process

1 reference

8 April 2019

Skeletal muscle hypertrophy is mediated by a Ca2+-dependent calcineurin signalling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of glycolytic process

1 reference

8 April 2019

Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI 8226

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

negative regulation of smooth muscle cell apoptotic process

1 reference

8 April 2019

Differential effects of insulin-like growth factor-1 and atheroma-associated cytokines on cell proliferation and apoptosis in plaque smooth muscle cells of symptomatic and asymptomatic patients with carotid stenosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

1 reference

8 April 2019

Skeletal muscle hypertrophy is mediated by a Ca2+-dependent calcineurin signalling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Insulin-like growth factor-I induces early osteoblast gene expression in human mesenchymal stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of cell growth involved in cardiac muscle cell development

positive regulation of cell population proliferation

4 references

8 April 2019

The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

One of two chondrocyte‐expressed isoforms of cartilage intermediate‐layer protein functions as an insulin‐like growth factor 1 antagonist

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Insulin-like growth factor-I augments erythropoietin-induced proliferation through enhanced tyrosine phosphorylation of STAT5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI 8226

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of osteoblast differentiation

1 reference

8 April 2019

Insulin-like growth factor-I induces early osteoblast gene expression in human mesenchymal stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

activation of protein kinase B activity

1 reference

8 April 2019

Cross-talk between integrin α6β4 and insulin-like growth factor-1 receptor (IGF1R) through direct α6β4 binding to IGF1 and subsequent α6β4-IGF1-IGF1R ternary complex formation in anchorage-independent conditions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

insulin-like growth factor receptor signaling pathway

2 references

8 April 2019

The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

8 April 2019

Cross-talk between integrin α6β4 and insulin-like growth factor-1 receptor (IGF1R) through direct α6β4 binding to IGF1 and subsequent α6β4-IGF1-IGF1R ternary complex formation in anchorage-independent conditions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

negative regulation of apoptotic process

1 reference

8 April 2019

Role of prolactin, growth hormone and insulin-like growth factor 1 in mammary gland involution in the dairy cow

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of tyrosine phosphorylation of STAT protein

1 reference

8 April 2019

Insulin-like growth factor-I augments erythropoietin-induced proliferation through enhanced tyrosine phosphorylation of STAT5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of gene expression

IEA

1 reference

8 April 2019

Involvement of insulin-like growth factor 1 receptor signaling in the amyloid-β peptide oligomers-induced p75 neurotrophin receptor protein expression in mouse hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

negative regulation of gene expression

1 reference

8 April 2019

Cartilage intermediate layer protein 1 (CILP1): A novel mediator of cardiac extracellular matrix remodelling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

cellular response to amyloid-beta

1 reference

8 April 2019

Involvement of insulin-like growth factor 1 receptor signaling in the amyloid-β peptide oligomers-induced p75 neurotrophin receptor protein expression in mouse hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

positive regulation of vascular associated smooth muscle cell proliferation

1 reference

8 April 2019

MicroRNA-1 regulates the proliferation of vascular smooth muscle cells by targeting insulin-like growth factor 1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

negative regulation of vascular associated smooth muscle cell apoptotic process

1 reference

8 April 2019

MicroRNA-1 regulates the proliferation of vascular smooth muscle cells by targeting insulin-like growth factor 1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

negative regulation of interleukin-1 beta production

1 reference

8 April 2019

Upregulation of microRNA-206 enhances lipopolysaccharide-induced inflammation and release of amyloid-β by targeting insulin-like growth factor 1 in microglia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

negative regulation of tumor necrosis factor production

1 reference

8 April 2019

Upregulation of microRNA-206 enhances lipopolysaccharide-induced inflammation and release of amyloid-β by targeting insulin-like growth factor 1 in microglia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

negative regulation of neuroinflammatory response

1 reference

8 April 2019

Upregulation of microRNA-206 enhances lipopolysaccharide-induced inflammation and release of amyloid-β by targeting insulin-like growth factor 1 in microglia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

negative regulation of amyloid-beta formation

1 reference

8 April 2019

Upregulation of microRNA-206 enhances lipopolysaccharide-induced inflammation and release of amyloid-β by targeting insulin-like growth factor 1 in microglia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05019

imported from Wikimedia project

Gene Atlas image

PBB GE IGF1 209541 at.png
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1 reference

1 reference

Insulin, conserved site

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stated in

Identifiers

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30 May 2020

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13 November 2019

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28 October 2013

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9 August 2016

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9 August 2016