(Q14889820)

Moesin tail domain superfamily

1 reference

FERM/acyl-CoA-binding protein superfamily

1 reference

PH-like domain superfamily

1 reference

FERM superfamily, second domain

1 reference

Ezrin/radixin/moesin

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Band 4.1 domain, protein family

1 reference

FERM central domain, protein family

1 reference

FERM, C-terminal PH-like domain, protein family

1 reference

FERM, N-terminal domain, protein family

1 reference

FERM domain, protein family

1 reference

FERM conserved site, protein family

1 reference

cytoskeletal protein binding

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

4 references

14 February 2019

Merlin inhibits growth hormone-regulated Raf-ERKs pathways by binding to Grb2 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

NF2deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

Merlin, the Product of the Nf2 Tumor Suppressor Gene, Is an Inhibitor of the p21-Activated Kinase, Pak1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

protein domain specific binding

ISO

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

Widespread but cell type-specific expression of the mouse neurofibromatosis type 2 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

JCV T-antigen interacts with the neurofibromatosis type 2 gene product in a transgenic mouse model of malignant peripheral nerve sheath tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

Localization and functional domains of the neurofibromatosis type II tumor suppressor, merlin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

Localization and functional domains of the neurofibromatosis type II tumor suppressor, merlin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

NF2deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

3 references

1 reference

14 February 2019

Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

cortical actin cytoskeleton

IEA

1 reference

14 February 2019

Magicin, a novel cytoskeletal protein associates with the NF2 tumor suppressor merlin and Grb2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

A growing family of Notch ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

3 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

JCV T-antigen interacts with the neurofibromatosis type 2 gene product in a transgenic mouse model of malignant peripheral nerve sheath tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

Localization and functional domains of the neurofibromatosis type II tumor suppressor, merlin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

protein-containing complex

IEA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

regulation of gliogenesis

ISO

biological process

1 reference

14 February 2019

Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

cell-cell junction organization

1 reference

14 February 2019

NF2deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

regulation of protein stability

1 reference

14 February 2019

Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

regulation of neural precursor cell proliferation

1 reference

14 February 2019

Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

regulation of protein localization to nucleus

1 reference

14 February 2019

Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

odontogenesis of dentin-containing tooth

1 reference

14 February 2019

Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

14 February 2019

Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

lens fiber cell differentiation

1 reference

14 February 2019

The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

regulation of cell population proliferation

1 reference

14 February 2019

NF2deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

positive regulation of cell differentiation

1 reference

14 February 2019

Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

negative regulation of MAPK cascade

1 reference

14 February 2019

Merlin inhibits growth hormone-regulated Raf-ERKs pathways by binding to Grb2 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators

hippocampus development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

regulation of neurogenesis

1 reference

14 February 2019

Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

negative regulation of cell population proliferation

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

regulation of apoptotic process

IEA

3 references

regulation of cell cycle

3 references

negative regulation of cell growth

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46662

1 reference

FERM conserved site

1 reference

FERM, C-terminal PH-like domain

1 reference

FERM central domain

1 reference

FERM, N-terminal

1 reference

Band 4.1 domain

1 reference

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016