(Q14901655)

http://www.ebi.ac.uk/interpro/protein/P18760

Cofilin 1

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P18760

membrane proteins

1 reference

based on heuristic

inferred from GOA cell component → membrane

Actin-depolymerising factor homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

2 references

actin filament binding

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

signaling receptor binding

1 reference

14 February 2019

Human LilrB2 is a β-amyloid receptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's model

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

1 reference

14 February 2019

The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

intracellular anatomical structure

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18760&geneProductId=UniProtKB:P18760

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

cortical actin cytoskeleton

TAS

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

lamellipodium membrane

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

3 references

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18760&geneProductId=UniProtKB:P18760

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18760&geneProductId=UniProtKB:P18760

16 September 2017

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18760&geneProductId=UniProtKB:P18760

1 reference

16 September 2017

Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18760&geneProductId=UniProtKB:P18760

1 reference

14 February 2019

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

The actin depolymerizing factor n-cofilin is essential for neural tube morphogenesis and neural crest cell migration

biological process

neural fold formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics

response to amino acid

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

actin filament organization

1 reference

14 February 2019

Tissue transglutaminase contributes to disease progression in the R6/2 Huntington's disease mouse model via aggregate-independent mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

1 reference

14 February 2019

Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics

protein phosphorylation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

neural crest cell migration

1 reference

14 February 2019

The actin depolymerizing factor n-cofilin is essential for neural tube morphogenesis and neural crest cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

establishment of cell polarity

1 reference

14 February 2019

Tissue transglutaminase contributes to disease progression in the R6/2 Huntington's disease mouse model via aggregate-independent mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

positive regulation of actin filament depolymerization

2 references

14 February 2019

Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

The switch-associated protein 70 (SWAP-70) bundles actin filaments and contributes to the regulation of F-actin dynamics

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

actin filament depolymerization

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

14 February 2019

The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

actin filament fragmentation

1 reference

14 February 2019

The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P18760

platelet degranulation

1 reference

18 July 2017

cytoskeleton organization

TAS

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

regulation of cell morphogenesis

3 references

regulation of dendritic spine morphogenesis

cell projection organization

1 reference

18 July 2017

Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P18760

negative regulation of cell size

ISO

1 reference

18 July 2017

Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P18760

response to organic cyclic compound

ISO

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

hippocampus development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

cellular response to ether

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18760

Actin-depolymerising factor homology domain

has part(s)

1 reference

stated in

InterPro Release 71.0