(Q14901975)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

Phosphorylation of NLRC4 is critical for inflammasome activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

Novel role of PKR in inflammasome activation and HMGB1 release

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

Syk is involved in NLRP3 inflammasome-mediated caspase-1 activation through adaptor ASC phosphorylation and enhanced oligomerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

A bacterial invasin induces macrophage apoptosis by binding directly to ICE

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

cysteine-type endopeptidase activity involved in execution phase of apoptosis

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

cysteine-type endopeptidase activity involved in apoptotic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

cysteine-type endopeptidase activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

IDA

scaffold protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

endopeptidase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

identical protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

cysteine-type endopeptidase activity involved in apoptotic signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

NLRP1 inflammasome complex

TAS

1 reference

8 April 2019

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

IPAF inflammasome complex

IDA

1 reference

8 April 2019

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

NLRP3 inflammasome complex

4 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

AIM2 inflammasome complex

4 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

3 references

21 June 2018

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

4 references

8 April 2019

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

protein-containing complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

protease inhibitor complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

regulation of apoptotic process

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

1 reference

8 April 2019

P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion

response to bacterium

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

membrane hyperpolarization

1 reference

8 April 2019

Cellular adaptation to anthrax lethal toxin-induced mitochondrial cholesterol enrichment, hyperpolarization, and reactive oxygen species generation through downregulating MLN64 in macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

1 reference

8 April 2019

Non-canonical inflammasome activation targets caspase-11

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

4 references

8 April 2019

Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

Inhibitory effects of chloride on the activation of caspase-1, IL-1beta secretion, and cytolysis by the P2X7 receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

Altered cytokine production in mice lacking P2X(7) receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

8 April 2019

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

1 reference

8 April 2019

CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

cellular response to mechanical stimulus

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion

regulation of autophagy

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

regulation of inflammatory response

1 reference

8 April 2019

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

interleukin-1 beta production

1 reference

8 April 2019

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

mitochondrial depolarization

IGI

1 reference

8 April 2019

Cellular adaptation to anthrax lethal toxin-induced mitochondrial cholesterol enrichment, hyperpolarization, and reactive oxygen species generation through downregulating MLN64 in macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

programmed necrotic cell death

1 reference

8 April 2019

Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

execution phase of apoptosis

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

positive regulation of I-kappaB kinase/NF-kappaB signaling

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

21 June 2018

ASC directs NF-kappaB activation by regulating receptor interacting protein-2 (RIP2) caspase-1 interactions

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29452&geneProductId=UniProtKB:P29452

microglial cell activation

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

response to organic cyclic compound

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

positive regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

positive regulation of circadian sleep/wake cycle, non-REM sleep

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

activation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

protein autoprocessing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

cellular response to lipopolysaccharide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

cellular response to organic substance

1 reference

8 April 2019

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

cellular response to interferon-gamma

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

apoptotic signaling pathway

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452

positive regulation of tumor necrosis factor-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29452