(Q14905611)

Winged helix-like DNA-binding domain superfamily

1 reference

Fork head domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Fork head domain conserved site1, protein family

1 reference

based on heuristic

inferred from protein domain or family

Fork head domain conserved site 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

sequence-specific DNA binding

4 references

8 April 2019

Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

DNA-binding transcription activator activity, RNA polymerase II-specific

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61850&geneProductId=UniProtKB:Q61850

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61850&geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

1 reference

24 April 2018

The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61850&geneProductId=UniProtKB:Q61850

Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures

chromatin DNA binding

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

DNA-binding transcription factor activity

6 references

8 April 2019

Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

Forkhead transcription factors regulate expression of the chemokine receptor CXCR4 in endothelial cells and CXCL12-induced cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

promoter-specific chromatin binding

1 reference

8 April 2019

Forkhead transcription factors regulate expression of the chemokine receptor CXCR4 in endothelial cells and CXCL12-induced cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

MFH-1, a new member of the fork head domain family, is expressed in developing mesenchyme

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

DNA-binding transcription factor activity, RNA polymerase II-specific

IBA

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

identical protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis

biological process

Notch signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

1 reference

8 April 2019

The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

embryonic skeletal system morphogenesis

1 reference

8 April 2019

Essential roles of the winged helix transcription factor MFH-1 in aortic arch patterning and skeletogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

skeletal system development

insulin receptor signaling pathway

2 references

3 references

8 April 2019

Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract

ureteric bud development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

positive regulation of cell migration involved in sprouting angiogenesis

1 reference

8 April 2019

The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

neural crest cell development

1 reference

8 April 2019

Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

paraxial mesoderm formation

1 reference

8 April 2019

The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

paraxial mesodermal cell fate commitment

1 reference

8 April 2019

The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

1 reference

8 April 2019

The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

1 reference

8 April 2019

Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

3 references

8 April 2019

Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

collagen fibril organization

1 reference

8 April 2019

Haploinsufficiency of the transcription factors FOXC1 and FOXC2 results in aberrant ocular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

glomerular mesangial cell development

1 reference

8 April 2019

Large-scale identification of genes implicated in kidney glomerulus development and function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

1 reference

8 April 2019

Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

positive regulation of integrin activation

1 reference

8 April 2019

The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

negative regulation of transcription by RNA polymerase II

IC

1 reference

8 April 2019

The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

cardiac muscle cell proliferation

1 reference

8 April 2019

Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development

lymph vessel development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61850&geneProductId=UniProtKB:Q61850

embryonic heart tube development

1 reference

8 April 2019

The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

positive regulation of endothelial cell migration

1 reference

8 April 2019

The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

multicellular organism development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

positive regulation of transcription, DNA-templated

4 references

8 April 2019

Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

ventricular cardiac muscle tissue morphogenesis

1 reference

8 April 2019

Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

Roles for the winged helix transcription factors MF1 and MFH1 in cardiovascular development revealed by nonallelic noncomplementation of null alleles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

Roles of forkhead transcription factor Foxc2 (MFH-1) and endothelin receptor A in cardiovascular morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

blood vessel remodeling

vascular endothelial growth factor receptor signaling pathway

1 reference

8 April 2019

The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development

blood vessel development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

positive regulation of vascular wound healing

1 reference

8 April 2019

The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

branching involved in blood vessel morphogenesis

1 reference

8 April 2019

Roles of forkhead transcription factor Foxc2 (MFH-1) and endothelin receptor A in cardiovascular morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

glomerular visceral epithelial cell differentiation

1 reference

8 April 2019

Large-scale identification of genes implicated in kidney glomerulus development and function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

3 references

8 April 2019

Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

embryonic cranial skeleton morphogenesis

1 reference

8 April 2019

The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

embryonic viscerocranium morphogenesis

1 reference

8 April 2019

Essential roles of the winged helix transcription factor MFH-1 in aortic arch patterning and skeletogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

camera-type eye development

1 reference

8 April 2019

Haploinsufficiency of the transcription factors FOXC1 and FOXC2 results in aberrant ocular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

glomerular endothelium development

1 reference

8 April 2019

Large-scale identification of genes implicated in kidney glomerulus development and function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

positive regulation of cell adhesion mediated by integrin

1 reference

8 April 2019

The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

regulation of organ growth

1 reference

8 April 2019

Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

cell population proliferation

Large-scale identification of genes implicated in kidney glomerulus development and function

metanephros development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

negative regulation of apoptotic process involved in outflow tract morphogenesis

1 reference

8 April 2019

Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

transcription by RNA polymerase II

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61850&geneProductId=UniProtKB:Q61850

positive regulation of transcription by RNA polymerase II

3 references

24 April 2018

Forkhead transcription factors regulate expression of the chemokine receptor CXCR4 in endothelial cells and CXCL12-induced cell migration

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61850&geneProductId=UniProtKB:Q61850

24 April 2018

The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61850&geneProductId=UniProtKB:Q61850

24 April 2018

The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61850&geneProductId=UniProtKB:Q61850

regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

14 February 2019

Roles for the winged helix transcription factors MF1 and MFH1 in cardiovascular development revealed by nonallelic noncomplementation of null alleles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

14 February 2019

Roles of forkhead transcription factor Foxc2 (MFH-1) and endothelin receptor A in cardiovascular morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

14 February 2019

Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

anatomical structure morphogenesis

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

positive regulation of transcription, DNA-templated

IBA

3 references

14 February 2019

Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

14 February 2019

Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

positive regulation of transcription by RNA polymerase II

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

14 February 2019

Forkhead transcription factors regulate expression of the chemokine receptor CXCR4 in endothelial cells and CXCL12-induced cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

14 February 2019

The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

14 February 2019

The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

positive regulation of transcription by RNA polymerase II

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

Forkhead transcription factors regulate expression of the chemokine receptor CXCR4 in endothelial cells and CXCL12-induced cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

8 April 2019

The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61850

negative regulation of cold-induced thermogenesis

3 references

Fork head domain conserved site 2

1 reference

Fork head domain

1 reference

Fork head domain conserved site1

1 reference