Wikidata

(Q15326775)

English

Period circadian clock 1

mammalian protein found in Mus musculus

  • Per1
  • period circadian protein homolog 1
  • circadian clock protein PERIOD 1
  • period homolog 1
  • circadian pacemaker protein Rigui
In more languages

Statements

molecular function
protein binding
determination method
IPI
15 references
retrieved
14 February 2019
stated in
A molecular mechanism for circadian clock negative feedback
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
retrieved
14 February 2019
stated in
A role for the circadian clock protein Per1 in the regulation of aldosterone levels and renal Na+ retention
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
retrieved
14 February 2019
stated in
Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
retrieved
14 February 2019
stated in
The polycomb group protein EZH2 is required for mammalian circadian clock function
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
retrieved
14 February 2019
stated in
Casein kinase 1 delta regulates the pace of the mammalian circadian clock
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
retrieved
14 February 2019
stated in
Direct association between mouse PERIOD and CKIepsilon is critical for a functioning circadian clock
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
retrieved
14 February 2019
stated in
A mammalian ortholog of Drosophila timeless, highly expressed in SCN and retina, forms a complex with mPER1
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
retrieved
14 February 2019
stated in
Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2.
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
retrieved
14 February 2019
stated in
Distinct roles of DBHS family members in the circadian transcriptional feedback loop
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
retrieved
14 February 2019
stated in
Molecular analysis of mammalian timeless
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
retrieved
14 February 2019
stated in
Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
retrieved
14 February 2019
stated in
CAVIN-3 regulates circadian period length and PER:CRY protein abundance and interactions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
retrieved
14 February 2019
stated in
High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
retrieved
14 February 2019
stated in
A mammalian ortholog of Drosophila timeless, highly expressed in SCN and retina, forms a complex with mPER1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
retrieved
14 February 2019
stated in
Machine learning helps identify CHRONO as a circadian clock component
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IPI
cell component
biological process
circadian rhythm
determination method
IEA
IEP
ISO
TAS
10 references
retrieved
14 February 2019
stated in
Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
TAS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
ISO
retrieved
14 February 2019
stated in
p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IEP
retrieved
14 February 2019
stated in
ID2 (inhibitor of DNA binding 2) is a rhythmically expressed transcriptional repressor required for circadian clock output in mouse liver
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IEP
retrieved
14 February 2019
stated in
Role of type II protein arginine methyltransferase 5 in the regulation of Circadian Per1 gene
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IEP
retrieved
14 February 2019
stated in
Disruption of CLOCK-BMAL1 transcriptional activity is responsible for aryl hydrocarbon receptor-mediated regulation of Period1 gene
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IEP
retrieved
14 February 2019
stated in
Histone acetyltransferase-dependent chromatin remodeling and the vascular clock
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IEP
retrieved
14 February 2019
stated in
Inducible cAMP early repressor regulates the Period 1 gene of the hepatic and adrenal clocks
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IEP
retrieved
14 February 2019
stated in
Dec1 and Dec2 expression is disrupted in the suprachiasmatic nuclei of Clock mutant mice
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IEP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IEA
negative regulation of transcription by RNA polymerase II
determination method
IBA
IDA
IMP
5 references
retrieved
14 February 2019
stated in
A role for the circadian clock protein Per1 in the regulation of the NaCl co-transporter (NCC) and the with-no-lysine kinase (WNK) cascade in mouse distal convoluted tubule cells
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IMP
retrieved
14 February 2019
stated in
A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IDA
retrieved
14 February 2019
stated in
Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IDA
retrieved
14 February 2019
stated in
Dec1 and Dec2 are regulators of the mammalian molecular clock
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IBA
circadian regulation of gene expression
determination method
IBA
IDA
IEA
IMP
ISO
ISS
6 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
ISO
retrieved
14 February 2019
stated in
Mouse Period1 (mPER1) acts as a circadian adaptor to entrain the oscillator to environmental light/dark cycles by regulating mPER2 protein
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IEA
retrieved
14 February 2019
stated in
The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors
GOA
curator
UniProt
UniProt protein ID
O35973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35973
determination method
IBA

Identifiers

 
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