(Q18027819)

English

IL2RA

protein-coding gene in the species Homo sapiens

CD25
IDDM10
IL2R
TCGFR
p55
IMD41
interleukin 2 receptor subunit alpha

In more languages

Statements

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

protein-coding gene

1 reference

Ensembl Release 87

Ensembl gene ID

ENSG00000134460

Protein IL2RA PDB 1z92.png
1,082 × 606; 308 KB

Structure de la protéine IL2RA. Basé sur l'identifiant PDB 1z92. (French)

0 references

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

Interleukin 2 receptor subunit alpha

1 reference

6 July 2017

UniProt protein ID

Interleukin-2 receptor subunit alpha

1 reference

UniProt protein ID

20 March 2016

language of work or name

genetic association

rheumatoid arthritis

determination method

genome-wide association study

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_7148&ncbiId=3559

http://www.genome.gov/gwastudies/index.cfm?gene=IL2RA

Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study

25 May 2020

type-1 diabetes

determination method

genome-wide association study

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_9744&ncbiId=3559

http://www.genome.gov/gwastudies/index.cfm?gene=IL2RA

1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data

25 May 2020

multiple sclerosis

determination method

genome-wide association study

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_2377&ncbiId=3559

http://www.genome.gov/gwastudies/index.cfm?gene=IL2RA

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci

25 May 2020

Crohn's disease

determination method

genome-wide association study

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_8778&ncbiId=3559

http://www.genome.gov/gwastudies/index.cfm?gene=IL2RA

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

25 May 2020

alopecia areata

determination method

genome-wide association study

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_986&ncbiId=3559

http://www.genome.gov/gwastudies/index.cfm?gene=IL2RA

Genome-wide association study in alopecia areata implicates both innate and adaptive immunity

25 May 2020

type 1 diabetes mellitus 10

1 reference

UniProt protein ID

13 August 2019

CD25 deficiency

1 reference

Open Targets Platform

24 August 2023

https://platform.opentargets.org/evidence/ENSG00000134460/MONDO_0011664

based on heuristic

inferred from an Open Targets association score over 0.7

human chromosome 10

genomic assembly

genome assembly GRCh38

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

strand orientation

genomic assembly

genome assembly GRCh38

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

6010689

human chromosome 10

genomic assembly

genome assembly GRCh38

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

6052652

human chromosome 10

genomic assembly

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

6104288

human chromosome 10

genomic assembly

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

6062370

human chromosome 10

genomic assembly

genome assembly GRCh38

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

cytogenetic location

10p15.1

1 reference

15 May 2022

360

1 reference

15 May 2022

Gene Atlas image

PBB GE IL2RA 211269 s at fs.png
732 × 530; 12 KB

0 references

PBB GE IL2RA 206341 at fs.png
732 × 530; 11 KB

0 references

1 reference

HomoloGene build68

360

1 reference

HomoloGene build68

360

1

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000134460

2

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000134460

3

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000134460

4

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000134460

5

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000134460

smooth muscle tissue

6

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000134460

7

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000134460

8

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000134460

ascending aorta

9

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000134460

upper lobe of left lung

10

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000134460

http://identifiers.org/ncbigene/3559

1 reference

Identifiers.org

http://www.ebi.ac.uk/miriam/main/collections/MIR:00000069

Identifiers

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

Ensembl gene ID

ENSG00000134460

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

Ensembl transcript ID

ENST00000447847

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

ENST00000256876

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

ENST00000379954

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

ENST00000379959

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

ENST00000644262

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

ENST00000649218

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000134460

HGNC gene symbol

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

Online Mendelian Inheritance in Man

19 August 2019

1 reference

based on heuristic

inferred by common HGNC mappings on source and on Wikidata

15 June 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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