(Q1977297)

English

Apolipoprotein C1

mammalian protein found in Homo sapiens

APOC1
apolipoprotein C-I

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

Apolipoprotein C-I

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P02654

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

phospholipase inhibitor activity

determination method

1 reference

8 April 2019

Apolipoprotein C-1 inhibits the hydrolysis by phospholipase A2 of phospholipids in liposomes and cell membranes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

phosphatidylcholine binding

determination method

1 reference

8 April 2019

Apolipoprotein C-1 inhibits the hydrolysis by phospholipase A2 of phospholipids in liposomes and cell membranes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

fatty acid binding

determination method

1 reference

8 April 2019

Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

phosphatidylcholine-sterol O-acyltransferase activator activity

determination method

1 reference

8 April 2019

Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

determination method

1 reference

8 April 2019

Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

endoplasmic reticulum

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

high-density lipoprotein particle

determination method

1 reference

8 April 2019

Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

biological process

lipid transport

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

chylomicron remnant clearance

determination method

1 reference

8 April 2019

Inhibitory effects of C apolipoproteins from rats and humans on the uptake of triglyceride-rich lipoproteins and their remnants by the perfused rat liver

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

negative regulation of fatty acid biosynthetic process

determination method

1 reference

8 April 2019

Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

lipid metabolism

determination method

1 reference

8 April 2019

Exact localization of the familial dysbetalipoproteinemia associated HpaI restriction site in the promoter region of the APOC1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

positive regulation of cholesterol esterification

determination method

1 reference

8 April 2019

Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

phospholipid efflux

determination method

1 reference

8 April 2019

Apolipoprotein specificity for lipid efflux by the human ABCAI transporter

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

cholesterol metabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

negative regulation of phosphatidylcholine catabolic process

determination method

1 reference

8 April 2019

Apolipoprotein C-1 inhibits the hydrolysis by phospholipase A2 of phospholipids in liposomes and cell membranes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

plasma lipoprotein particle remodeling

determination method

1 reference

8 April 2019

Human apolipoprotein C-I accounts for the ability of plasma high density lipoproteins to inhibit the cholesteryl ester transfer protein activity

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

negative regulation of very-low-density lipoprotein particle clearance

determination method

1 reference

8 April 2019

Mechanisms of inhibition by apolipoprotein C of apolipoprotein E-dependent cellular metabolism of human triglyceride-rich lipoproteins through the low density lipoprotein receptor pathway

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

regulation of cholesterol transport

determination method

1 reference

8 April 2019

Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

negative regulation of receptor-mediated endocytosis

determination method

1 reference

8 April 2019

Mechanisms of inhibition by apolipoprotein C of apolipoprotein E-dependent cellular metabolism of human triglyceride-rich lipoproteins through the low density lipoprotein receptor pathway

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

high-density lipoprotein particle remodeling

determination method

1 reference

8 April 2019

Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

cholesterol efflux

determination method

1 reference

8 April 2019

Apolipoprotein specificity for lipid efflux by the human ABCAI transporter

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

negative regulation of cholesterol transport

determination method

1 reference

8 April 2019

Human apolipoprotein C-I accounts for the ability of plasma high density lipoproteins to inhibit the cholesteryl ester transfer protein activity

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

negative regulation of lipoprotein lipase activity

determination method

1 reference

8 April 2019

Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

negative regulation of lipid catabolic process

determination method

1 reference

8 April 2019

Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

triglyceride metabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

negative regulation of lipid metabolic process

determination method

1 reference

8 April 2019

Effect of serum and C-apoproteins from very low density lipoproteins on human postheparin plasma hepatic lipase

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

positive regulation of catalytic activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

lipoprotein metabolic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02654

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000465356

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000465356

ENSP00000468029

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000468029

ENSP00000465190

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000465190

ENSP00000465710

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000465710

ENSP00000466146

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000466146

ENSP00000466227

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000466227

ENSP00000467368

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000467368

ENSP00000467504

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000467504

ENSP00000468276

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000468276

1 reference

Freebase Data Dumps

publication date

28 October 2013

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q1977297&oldid=2022903549"