(Q20948663)

Ixazomib (English)

19 October 2016

C₁₄H₁₉BCl₂N₂O₄

1 reference

MLN2238 (English)

20 November 2016

B(C(CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O

1 reference

MLN2238 (English)

20 November 2016

B([C@H](CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O

1 reference

World Health Organisation international non-proprietary name

MLN2238 (English)

20 November 2016

1 reference

14 February 2018

ixazomib (English)

1 reference

ixazomib (English)

medical condition treated

19 October 2016

amyloidosis

1 reference

Drug Indications Extracted from FAERS

2 October 2018

20 November 2015

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/71050168A2

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/208462s001lbl.pdf

physically interacts with

Proteasome 20S subunit beta 5

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

8450

Proteasome 20S subunit alpha 3

17 August 2016

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

Proteasome 20S subunit beta 2

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

Proteasome 20S subunit alpha 2

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

Proteasome 20S subunit beta 8

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

Proteasome 26S subunit, non-ATPase 1

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

Proteasome subunit beta 11

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

Proteasome 20S subunit alpha 7

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

Proteasome 20S subunit alpha 5

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

Proteasome 26S subunit, non-ATPase 14

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

Proteasome 20S subunit beta 5

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

Proteasome 20S subunit alpha 6

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

Proteasome subunit beta 1

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

Proteasome 20S subunit beta 10

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

Proteasome 20S subunit alpha 8

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

Proteasome 20S subunit beta 6

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

LiverTox likelihood score

LiverTox toxicity likelihood category E*

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Ixazomib

1 June 2017

1 reference

Medical Subject Headings

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

C548400

InChI=1S/C14H19BCl2N2O4/c1-8(2)5-12(15(22)23)19-13(20)7-18-14(21)10-6-9(16)3-4-11(10)17/h3-4,6,8,12,22-23H,5,7H2,1-2H3,(H,18,21)(H,19,20)/t12-/m0/s1

15 March 2018

Identifiers

InChI

1 reference

MXAYKZJJDUDWDS-LBPRGKRZSA-N

MLN2238 (English)

20 November 2016

2 references

MLN2238 (English)

20 November 2016

ChEBI release 2020-09-01

CAS Registry Number

1072833-77-2

2 references

MXAYKZJJDUDWDS-LBPRGKRZSA-N

ixazomib (English)

20 November 2016

9 April 2021

https://commonchemistry.cas.org/detail?cas_rn=1072833-77-2

1 reference

ixazomib (English)

20 November 2016

1 reference

MLN2238 (English)

20 November 2016

Reaxys registry number

18302358

1 reference

ixazomib (English)

19 October 2016

mapping relation type

1 reference

ixazomib (English)

19 October 2016

1 reference

CHEMBL2141296 (English)

20 November 2016

1 reference

0 references

810-246-8

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.238.319

27 December 2018

ECHA Substance Infocard ID

[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methyl-butyl]boronic acid (English)

quotation

CAS no.: 1072833-77-2 (English)

100.238.319

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.238.319

20 December 2018

Guide to Pharmacology Ligand ID

[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methyl-butyl]boronic acid (English)

quotation

CAS no.: 1072833-77-2 (English)

ATC code

L01XX50

0 references

8450

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

8450

ixazomib (English)

20 November 2016

1 reference

Medical Subject Headings

14 March 2018

1 reference

ixazomib (English)

20 November 2016

1 reference

Ixazomib (English)

20 November 2016

1 reference

ixazomib (English)

MedlinePlus drug identifier

20 November 2016

a616008

0 references

PatientsLikeMe treatment ID

0 references

1 reference

ixazomib (English)

20 November 2016

0 references

1 reference

1 reference

Google Knowledge Graph ID

ixazomib (English)

19 October 2016

0 references

/g/11b86wvrmf

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

5LF7 (English)

19 October 2016

1 reference