(Q21104987)

DHS-like NAD/FAD-binding domain superfamily

1 reference

stated in

Sirtuin, catalytic core small domain superfamily

1 reference

stated in

Sirtuin family, catalytic core domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

NAD-dependent protein deacetylase activity

1 reference

8 April 2019

Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

5 references

8 April 2019

Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

2 references

NAD+ ADP-ribosyltransferase activity

8 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

Sirtuin functions in health and disease

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

1 reference

8 April 2019

Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

mitochondrial inner membrane

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

IDA

biological process

protein ADP-ribosylation

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

Sirtuin functions in health and disease

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

regulation of glutamine family amino acid metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

negative regulation of fatty acid oxidation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

SIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

cellular response to DNA damage stimulus

ISS

negative regulation of protein processing involved in protein targeting to mitochondrion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

negative regulation of cardiac muscle cell apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

cellular response to hypoxia

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

mitochondrion organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6E7

TAS

protein deacetylation

1 reference

8 April 2019

http://www.uniprot.org/uniprot/Q9Y6E7.txt?version=124

EC enzyme number

2.4.2.-

1 reference

14 November 2015

has part(s)

Sirtuin family, catalytic core domain

1 reference

stated in