Wikidata

(Q21105865)

English

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

mammalian protein found in Homo sapiens

  • deoxynucleoside triphosphate triphosphohydrolase SAMHD1
  • SAM domain and HD domain-containing protein 1
  • dNTPase
  • dendritic cell-derived IFNG-induced protein
  • SAMHD1
  • MOP-5
  • DCIP
  • monocyte protein 5
  • SAM domain and HD domain 1
In more languages

Statements

molecular function
protein binding
determination method
IPI
6 references
retrieved
1 January 2018
stated in
SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.
GOA
curator
UniProt
UniProt protein ID
Q9Y3Z3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3Z3
determination method
IPI
retrieved
1 January 2018
stated in
SAMHD1 acts at stalled replication forks to prevent interferon induction
GOA
curator
UniProt
UniProt protein ID
Q9Y3Z3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3Z3
determination method
IPI
retrieved
1 January 2018
stated in
The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation
GOA
curator
UniProt
UniProt protein ID
Q9Y3Z3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3Z3
determination method
IPI
retrieved
1 January 2018
stated in
CD81 association with SAMHD1 enhances HIV-1 reverse transcription by increasing dNTP levels.
GOA
curator
UniProt
UniProt protein ID
Q9Y3Z3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3Z3
determination method
IPI
retrieved
1 January 2018
stated in
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3Z3
determination method
IPI
retrieved
1 January 2018
stated in
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3Z3
determination method
IPI
cell component
biological process
defense response to virus
determination method
IBA
IDA
IEA
IMP
6 references
retrieved
1 January 2018
stated in
Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response
GOA
curator
UniProt
UniProt protein ID
Q9Y3Z3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3Z3
determination method
IMP
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y3Z3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3Z3
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3Z3
determination method
IEA
retrieved
1 January 2018
stated in
Impaired dNTPase activity of SAMHD1 by phosphomimetic mutation of Thr-592
GOA
curator
UniProt
UniProt protein ID
Q9Y3Z3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3Z3
determination method
IDA
retrieved
1 January 2018
stated in
The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation
GOA
curator
UniProt
UniProt protein ID
Q9Y3Z3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3Z3
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3Z3
determination method
IBA

Identifiers

MeSH descriptor ID
D000076106
subject named as
SAM Domain and HD Domain-Containing Protein 1
0 references
Ensembl protein ID
Freebase ID
/m/04087rc
0 references
PDB structure ID
 
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