(Q21108487)

GPCR, family 2, parathyroid hormone receptor

1 reference

G protein-coupled receptor

1 reference

Transporter Classification Database ID

9.A.14.4.11

2 October 2019

hierarchical database ID heuristic

GPCR, family 2, extracellular hormone receptor domain, protein family

1 reference

inferred from protein domain or family

GPCR, family 2-like

1 reference

inferred from protein domain or family

GPCR, family 2, secretin-like, conserved site, protein family

1 reference

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

parathyroid hormone receptor activity

5 references

27 March 2018

Human osteoclast-like cells are formed from peripheral blood mononuclear cells in a coculture with SaOS-2 cells transfected with the parathyroid hormone (PTH)/PTH-related protein receptor gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03431&geneProductId=UniProtKB:Q03431

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03431&geneProductId=UniProtKB:Q03431

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03431&geneProductId=UniProtKB:Q03431

27 March 2018

Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03431&geneProductId=UniProtKB:Q03431

27 March 2018

Cloning and functional expression of a human parathyroid hormone receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03431&geneProductId=UniProtKB:Q03431

signal transducer activity

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03431&geneProductId=UniProtKB:Q03431

Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides

protein self-association

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

2 references

8 April 2019

Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

β-catenin regulates parathyroid hormone/parathyroid hormone-related protein receptor signals and chondrocyte hypertrophy through binding to the intracellular C-terminal region of the receptor

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

transmembrane signaling receptor activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

protein homodimerization activity

1 reference

8 April 2019

Characterization of a PTH1R missense mutation responsible for Jansen type metaphyseal chondrodysplasia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

parathyroid hormone receptor activity

6 references

8 April 2019

Human osteoclast-like cells are formed from peripheral blood mononuclear cells in a coculture with SaOS-2 cells transfected with the parathyroid hormone (PTH)/PTH-related protein receptor gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

Cloning and functional expression of a human parathyroid hormone receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

G protein-coupled peptide receptor activity

IBA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

IBA

peptide hormone binding

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

2 references

intracellular anatomical structure

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03431&geneProductId=UniProtKB:Q03431

brush border membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

integral component of plasma membrane

3 references

8 April 2019

Novel, missense and loss-of-function mutations in the sodium/iodide symporter gene causing iodide transport defect in three Japanese patients

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

Cloning and functional expression of a human parathyroid hormone receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

G protein-coupled receptor signaling pathway

biological process

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

Novel, missense and loss-of-function mutations in the sodium/iodide symporter gene causing iodide transport defect in three Japanese patients

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

chondrocyte differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

positive regulation of cytosolic calcium ion concentration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

2 references

8 April 2019

Human osteoclast-like cells are formed from peripheral blood mononuclear cells in a coculture with SaOS-2 cells transfected with the parathyroid hormone (PTH)/PTH-related protein receptor gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

cellular calcium ion homeostasis

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03431&geneProductId=UniProtKB:Q03431

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

cell surface receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

positive regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

osteoblast development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

negative regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

adenylate cyclase-activating G protein-coupled receptor signaling pathway

4 references

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

Cloning and functional expression of a human parathyroid hormone receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

8 April 2019

Characterization of a PTH1R missense mutation responsible for Jansen type metaphyseal chondrodysplasia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03431

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4448

English

GPCR, family 2, extracellular hormone receptor domain

17 August 2016

has part(s)

1 reference

GPCR, family 2, secretin-like, conserved site

1 reference

GPCR, family 2-like

1 reference

Identifiers

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

Transporter Classification Database ID

English

9.A.14.4.11

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023