(Q21110148)

English

SH2B adaptor protein 3

mammalian protein found in Homo sapiens

lymphocyte-specific adapter protein Lnk
Lymphocyte adapter protein
signal transduction protein Lnk
SH2B adapter protein 3
SH2B3

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Statements

1 reference

13 November 2019

SH2 domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UQQ2

PH-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UQQ2

SH2B adapter protein 3

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UQQ2

Phenylalanine zipper superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UQQ2

pleckstrin homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH2B3, SH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Phenylalanine zipper, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

signaling adaptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQQ2

determination method

IEA

transmembrane receptor protein tyrosine kinase adaptor activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQQ2

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQQ2

determination method

IEA

positive regulation of signal transduction

1 reference

8 April 2019

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQQ2

determination method

IEA

intracellular signal transduction

1 reference

24 April 2018

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQQ2&geneProductId=UniProtKB:Q9UQQ2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQQ2

determination method

TAS

embryonic hemopoiesis

1 reference

10 September 2018

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQQ2&geneProductId=UniProtKB:Q9UQQ2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQQ2

determination method

IEA

transmembrane receptor protein tyrosine kinase signaling pathway

1 reference

8 April 2019

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQQ2

determination method

IEA

thrombopoietin-mediated signaling pathway

4 references

8 April 2019

LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQQ2

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQQ2

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQQ2

8 April 2019

Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQQ2

determination method

IDA

negative regulation of receptor signaling pathway via JAK-STAT

1 reference

8 April 2019

Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQQ2

determination method

IMP

erythrocyte development

1 reference

8 April 2019

Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQQ2

determination method

IMP

negative regulation of response to cytokine stimulus

1 reference

8 April 2019

Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQQ2

determination method

IMP

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

(Q21110148)

SH2B adaptor protein 3

Statements

Identifiers

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