Wikidata

(Q21111463)

English

RB transcriptional corepressor 1

mammalian protein found in Homo sapiens

  • exon 17 tumor GOS561 substitution mutation causes premature stop
  • GOS563 exon 17 substitution mutation causes premature stop
  • p105-Rb
  • retinoblastoma-associated protein
  • retinoblastoma suspectibility protein
  • pRb
  • RB1
  • pp110
  • prepro-retinoblastoma-associated protein
  • Rb
  • retinoblastoma 1
  • protein phosphatase 1, regulatory subunit 130
In more languages

Statements

molecular function
protein binding
determination method
IPI
85 references
retrieved
8 April 2019
stated in
A novel Rb- and p300-binding protein inhibits transactivation by MyoD
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Methylation of the retinoblastoma tumor suppressor by SMYD2
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Phosphorylated retinoblastoma protein stimulates DNA polymerase alpha
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Rb inhibits the intrinsic kinase activity of TATA-binding protein-associated factor TAFII250
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Physical interaction between pRb and cdk9/cyclinT2 complex
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
L3MBTL1, a histone-methylation-dependent chromatin lock
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The de-ubiquitinating enzyme Unp interacts with the retinoblastoma protein
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
RBP95, a novel leucine zipper protein, binds to the retinoblastoma protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Association of human Pur alpha with the retinoblastoma protein, Rb, regulates binding to the single-stranded DNA Pur alpha recognition element
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Direct binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Two distinct and frequently mutated regions of retinoblastoma protein are required for binding to SV40 T antigen
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Protein Phosphatase 1 binds strongly to the retinoblastoma protein but not to p107 or p130 in vitro and in vivo
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Binding of an interferon-inducible protein (p202) to the retinoblastoma protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Roles for APIS and the 20S proteasome in adenovirus E1A-dependent transcription
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
A comprehensive resource of interacting protein regions for refining human transcription factor networks
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
p53 family members in myogenic differentiation and rhabdomyosarcoma development
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Shigella flexneri type III secretion system effectors OspB and OspF target the nucleus to downregulate the host inflammatory response via interactions with retinoblastoma protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Structure of the oncoprotein gankyrin in complex with S6 ATPase of the 26S proteasome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
LEDGF (p75) promotes DNA-end resection and homologous recombination
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Rb-Raf-1 interaction disruptor RRD-251 induces apoptosis in metastatic melanoma cells and synergizes with dacarbazine
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Proapoptotic function of the retinoblastoma tumor suppressor protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
HAUSP, a novel deubiquitinase for Rb - MDM2 the critical regulator
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
LEK1 is a potential inhibitor of pocket protein-mediated cellular processes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
DNA-damage-responsive acetylation of pRb regulates binding to E2F-1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Phospho-tyrosine dependent protein-protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Kras(G12D) and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Modulation of allostery by protein intrinsic disorder
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Targeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein. Structural modularity, intrinsic disorder and phosphorylation of human papillomavirus E7
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
A DNA polymerase alpha accessory protein exhibits structural and functional similarities to SV40 large tumor antigen
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The arginine methyltransferase PRMT2 binds RB and regulates E2F function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Interactions between activating signal cointegrator-2 and the tumor suppressor retinoblastoma in androgen receptor transactivation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Interaction between the retinoblastoma protein and the oncoprotein MDM2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
EBV-encoded EBNA-6 binds and targets MRS18-2 to the nucleus, resulting in the disruption of pRb-E2F1 complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Cyclin-binding motifs are essential for the function of p21CIP1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Mitogen-activated protein kinase p38 and retinoblastoma protein signalling is required for DNA damage-mediated formation of senescence-associated heterochromatic foci in tumour cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Cyclin C/cdk3 promotes Rb-dependent G0 exit
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The protein interaction landscape of the human CMGC kinase group
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
A limited screen for protein interactions reveals new roles for protein phosphatase 1 in cell cycle control and apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The region of the HPV E7 oncoprotein homologous to adenovirus E1a and Sv40 large T antigen contains separate domains for Rb binding and casein kinase II phosphorylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The functional interactome landscape of the human histone deacetylase family
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Purification and characterization of human papillomavirus type 16 E7 protein with preferential binding capacity to the underphosphorylated form of retinoblastoma gene product
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The adenovirus E1A oncoprotein recruits the cellular TRRAP/GCN5 histone acetyltransferase complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Direct suppression of Stat1 function during adenoviral infection
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Retinoblastoma protein represses transcription by recruiting a histone deacetylase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Interaction of the HPV E7 proteins with the pCAF acetyltransferase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Effects of MdmX on Mdm2-mediated downregulation of pRB
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Ebp1, an ErbB-3 binding protein, interacts with Rb and affects Rb transcriptional regulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Retinoblastoma protein recruits histone deacetylase to repress transcription
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
The rubella virus putative replicase interacts with the retinoblastoma tumor suppressor protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
retrieved
8 April 2019
stated in
Prohibitin, a protein downregulated by androgens, represses androgen receptor activity
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IPI
cell component
biological process
negative regulation of transcription, DNA-templated
determination method
IDA
TAS
IEA
6 references
retrieved
8 April 2019
stated in
The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IEA
retrieved
8 April 2019
stated in
HMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase IIalpha
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IDA
retrieved
8 April 2019
stated in
Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb
GOA
curator
UniProt
UniProt protein ID
P06400
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IDA
retrieved
8 April 2019
stated in
Prohibitin requires Brg-1 and Brm for the repression of E2F and cell growth
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06400
determination method
IDA

Identifiers

Freebase ID
/m/08dc4r
0 references
PDB structure ID
 
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                  Retrieved from "https://www.wikidata.org/w/index.php?title=Q21111463&oldid=2022945740"