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(Q21114343)
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English
Origin recognition complex subunit 1
mammalian protein found in Homo sapiens
ORC1
origin recognition complex, subunit 1 homolog
replication control protein 1
origin recognition complex subunit 1
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q13415
part of
Origin recognition complex, subunit 1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q13415
P-loop containing nucleoside triphosphate hydrolase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q13415
ATPase, AAA-type, core domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
AAA proteins
1 reference
based on heuristic
inferred from protein domain or family
Cdc6, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Bromo adjacent homology (BAH) domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q13415
encoded by
ORC1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q13415
molecular function
DNA binding
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
Conserved initiator proteins in eukaryotes
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q13415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IEA
nucleotide binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q13415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IEA
chromatin binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IEA
protein binding
determination method
IPI
8 references
retrieved
8 April 2019
stated in
A structural role for ATP in the formation and stability of the human origin recognition complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IPI
retrieved
8 April 2019
stated in
ORC binding to TRF2 stimulates OriP replication
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IPI
retrieved
8 April 2019
stated in
RNA-dependent recruitment of the origin recognition complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IPI
retrieved
8 April 2019
stated in
The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndrome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IPI
retrieved
8 April 2019
stated in
ATP-dependent assembly of the human origin recognition complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IPI
retrieved
8 April 2019
stated in
Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IPI
retrieved
8 April 2019
stated in
Self-assembling protein microarrays
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IPI
ATP binding
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q13415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IEA
DNA replication origin binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IBA
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q13415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IEA
cell component
nuclear origin of replication recognition complex
determination method
IDA
2 references
retrieved
17 October 2017
stated in
A WD-repeat protein stabilizes ORC binding to chromatin
GOA
curator
UniProt
UniProt protein ID
Q13415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13415&geneProductId=UniProtKB:Q13415
determination method
IDA
retrieved
17 October 2017
stated in
Nucleosome-interacting proteins regulated by DNA and histone methylation
GOA
curator
UniProt
UniProt protein ID
Q13415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13415&geneProductId=UniProtKB:Q13415
determination method
IDA
plasma membrane
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IDA
nucleolus
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IDA
origin recognition complex
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
ATP-dependent assembly of the human origin recognition complex
GOA
curator
UniProt
UniProt protein ID
Q13415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IDA
nucleus
determination method
IDA
IEA
TAS
3 references
retrieved
8 April 2019
stated in
Conserved initiator proteins in eukaryotes
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q13415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IDA
nucleoplasm
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
TAS
cytosol
determination method
IDA
TAS
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IDA
nuclear origin of replication recognition complex
determination method
IBA
IDA
3 references
retrieved
8 April 2019
stated in
Nucleosome-interacting proteins regulated by DNA and histone methylation
GOA
curator
UniProt
UniProt protein ID
Q13415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IDA
retrieved
8 April 2019
stated in
A WD-repeat protein stabilizes ORC binding to chromatin
GOA
curator
UniProt
UniProt protein ID
Q13415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IBA
biological process
G1 phase
determination method
TAS
1 reference
retrieved
17 October 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13415&geneProductId=UniProtKB:Q13415
determination method
TAS
DNA replication
determination method
TAS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q13415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IEA
regulation of transcription involved in G1/S transition of mitotic cell cycle
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
TAS
DNA replication initiation
determination method
TAS
1 reference
retrieved
17 October 2017
stated in
Conserved initiator proteins in eukaryotes
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13415&geneProductId=UniProtKB:Q13415
determination method
TAS
G1/S transition of mitotic cell cycle
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
TAS
mitotic cell cycle
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IBA
DNA replication initiation
determination method
IBA
TAS
2 references
retrieved
8 April 2019
stated in
Conserved initiator proteins in eukaryotes
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
TAS
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IBA
mitotic DNA replication checkpoint signaling
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13415
determination method
IBA
exact match
https://identifiers.org/uniprot:Q13415
1 reference
stated in
Identifiers.org
UniProt protein ID
Q13415
reference URL
https://registry.identifiers.org/registry/uniprot
http://purl.uniprot.org/uniprot/Q13415
1 reference
stated in
Identifiers.org
UniProt protein ID
Q13415
reference URL
https://registry.identifiers.org/registry/uniprot
https://www.ncbi.nlm.nih.gov/protein/Q13415
1 reference
stated in
Identifiers.org
UniProt protein ID
Q13415
reference URL
https://registry.identifiers.org/registry/uniprot
has part(s)
ATPase, AAA-type, core
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q13415
Cdc6, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q13415
Bromo adjacent homology (BAH) domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q13415
AAA+ ATPase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q13415
Identifiers
RefSeq protein ID
NP_001177747
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
4998
NP_001177748
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
4998
NP_004144
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
4998
XP_011539829
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
4998
XP_016856877
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
4998
XP_016856878
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
4998
UniProt protein ID
Q13415
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q13415
Ensembl protein ID
ENSP00000360621
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000360621
ENSP00000360623
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000360623
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