(Q21114850)

Protein kinase-like domain superfamily

1 reference

protein kinase C, alpha/beta/gamma types

1 reference

auxiliary protein involved in transmembrane transport

1 reference

Transporter Classification Database ID

8.A.104.1.4

2 October 2019

hierarchical database ID heuristic

Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family

1 reference

Protein kinase, C-terminal domain, protein family

1 reference

C2 domain, protein family

1 reference

Diacylglycerol/phorbol-ester binding domain, protein family

1 reference

AGC-kinase, C-terminal domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Classical Protein Kinase C beta, catalytic domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

protein kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

protein kinase C activity

Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

histone binding

1 reference

8 April 2019

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

zinc ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

calcium channel regulator activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

chromatin binding

1 reference

8 April 2019

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

protein serine/threonine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05771&geneProductId=UniProtKB:P05771

5 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05771&geneProductId=UniProtKB:P05771

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05771&geneProductId=UniProtKB:P05771

17 October 2017

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05771&geneProductId=UniProtKB:P05771

17 October 2017

Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05771&geneProductId=UniProtKB:P05771

EXP

protein binding

3 references

8 April 2019

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

8 April 2019

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

8 April 2019

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

androgen receptor binding

1 reference

8 April 2019

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

nuclear receptor coactivator activity

1 reference

8 April 2019

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

histone kinase activity (H3-T6 specific)

1 reference

8 April 2019

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

protein kinase C binding

1 reference

8 April 2019

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

calcium-dependent protein kinase C activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05771&geneProductId=UniProtKB:P05771

1 reference

1 January 2018

protein serine/threonine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

IBA

8 April 2019

Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

EXP

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

8 April 2019

Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

extracellular exosome

1 reference

17 October 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05771&geneProductId=UniProtKB:P05771

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

8 April 2019

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

calyx of Held

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

extracellular exosome

HDA

1 reference

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

HDA

presynaptic cytosol

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

cellular response to carbohydrate stimulus

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

response to hypoxia

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05771&geneProductId=UniProtKB:P05771

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05771&geneProductId=UniProtKB:P05771

1 reference

17 October 2017

adaptive immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

immune system process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

cellular calcium ion homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05771&geneProductId=UniProtKB:P05771

1 reference

17 October 2017

platelet activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

protein phosphorylation

Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

negative regulation of insulin receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

mitotic nuclear membrane disassembly

ISS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

peptidyl-serine phosphorylation

IBA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

IBA

calcium ion transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

signal transduction

NAS

1 reference

8 April 2019

Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

NAS

lipoprotein transport

1 reference

8 April 2019

Inhibition of protein kinase Cbeta prevents foam cell formation by reducing scavenger receptor A expression in human macrophages

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

regulation of myeloid cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

chromatin organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

1 reference

8 April 2019

presynaptic modulation of chemical synaptic transmission

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

positive regulation of nucleic acid-templated transcription

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

regulation of synaptic vesicle exocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05771

physically interacts with

ingenol mebutate

1 reference

7443

17 August 2016

1 reference

8142

17 August 2016

1 reference

5693

17 August 2016

1 reference

5263

English

object of statement has role

17 August 2016

sotrastaurin

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL565612

gsk-690693

object of statement has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL494089

has part(s)

protein kinase, C-terminal

1 reference

protein kinase domain

1 reference

protein kinase, ATP binding site

1 reference

diacylglycerol/phorbol-ester binding

1 reference

protein kinase C-like, phorbol ester/diacylglycerol-binding domain

1 reference

C2 domain

1 reference

serine/threonine-protein kinase, active site

1 reference

AGC-kinase, C-terminal

1 reference

Classical Protein Kinase C beta, catalytic domain

1 reference

D08.811.913.696.620.682.700.725.049

Identifiers

MeSH descriptor ID

D064546

subject named as

Protein Kinase C beta

0 references

MeSH tree code

0 references

D12.776.476.563.725.049

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

4 August 2016

Transporter Classification Database ID

English

8.A.104.1.4

2 references

Transporter Classification database

13 March 2020

Transporter Classification database