Wikidata

(Q21116502)

English

AKT serine/threonine kinase 2

mammalian protein found in Homo sapiens

  • putative v-akt murine thymoma viral oncoprotein 2
  • protein kinase Akt-2
  • PKB beta
  • protein kinase B beta
  • rac protein kinase beta
  • v-akt murine thymoma viral oncogene homolog 2
  • murine thymoma viral (v-akt) homolog-2
  • AKT2
  • RAC-beta serine/threonine-protein kinase
  • RAC-PK-beta
In more languages

Statements

molecular function
protein serine/threonine kinase activity
determination method
IDA
TAS
IEA
8 references
retrieved
21 June 2018
stated in
Akt1 and Akt2: differentiating the aktion
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31751&geneProductId=UniProtKB:P31751
determination method
TAS
retrieved
21 June 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31751&geneProductId=UniProtKB:P31751
determination method
TAS
retrieved
21 June 2018
stated in
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31751&geneProductId=UniProtKB:P31751
determination method
TAS
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31751&geneProductId=UniProtKB:P31751
determination method
IEA
retrieved
21 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31751&geneProductId=UniProtKB:P31751
determination method
IEA
retrieved
21 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31751&geneProductId=UniProtKB:P31751
determination method
IEA
retrieved
21 June 2018
stated in
Kinetic mechanism of AKT/PKB enzyme family
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31751&geneProductId=UniProtKB:P31751
determination method
IDA
retrieved
21 June 2018
stated in
The protooncogene TCL1 is an Akt kinase coactivator
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31751&geneProductId=UniProtKB:P31751
determination method
IDA
protein binding
determination method
IPI
13 references
retrieved
8 April 2019
stated in
The protooncogene TCL1 is an Akt kinase coactivator
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IPI
retrieved
8 April 2019
stated in
A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IPI
retrieved
8 April 2019
stated in
Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IPI
retrieved
8 April 2019
stated in
Interactions between GIPC-APPL and GIPC-TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IPI
retrieved
8 April 2019
stated in
The E3 ligase TRAF6 regulates Akt ubiquitination and activation
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IPI
retrieved
8 April 2019
stated in
Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IPI
retrieved
8 April 2019
stated in
The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IPI
retrieved
8 April 2019
stated in
Ankrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H(2)O(2)
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IPI
retrieved
8 April 2019
stated in
Systematic Analysis Reveals Elongation Factor 2 and α-Enolase as Novel Interaction Partners of AKT2
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IPI
retrieved
8 April 2019
stated in
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IPI
retrieved
8 April 2019
stated in
Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IPI
retrieved
8 April 2019
stated in
Vimentin is a novel AKT1 target mediating motility and invasion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IPI
retrieved
8 April 2019
stated in
APPL1, APPL2, Akt2 and FOXO1a interact with FSHR in a potential signaling complex
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IPI
protein serine/threonine kinase activity
determination method
IBA
IDA
IEA
TAS
8 references
retrieved
8 April 2019
stated in
Akt1 and Akt2: differentiating the aktion
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
TAS
retrieved
8 April 2019
stated in
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IEA
retrieved
8 April 2019
stated in
Kinetic mechanism of AKT/PKB enzyme family
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IDA
retrieved
8 April 2019
stated in
The protooncogene TCL1 is an Akt kinase coactivator
GOA
curator
UniProt
UniProt protein ID
P31751
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31751
determination method
IBA
cell component
biological process

Identifiers

Ensembl protein ID
PDB structure ID
 
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