(Q21117438)

DNA damage-binding protein 2

1 reference

WD40-repeat-containing domain superfamily

1 reference

WD40 repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

WD40 repeat, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

ubiquitin-protein transferase activity

1 reference

8 April 2019

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

protein binding

11 references

8 April 2019

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

DDB, a Putative DNA Repair Protein, Can Function as a Transcriptional Partner of E2F1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

damaged DNA binding

Characterization of a human DNA damage binding protein implicated in xeroderma pigmentosum E

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92466&geneProductId=UniProtKB:Q92466

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92466&geneProductId=UniProtKB:Q92466

24 April 2018

24 April 2018

Monoubiquitinated Histone H2A Destabilizes Photolesion-containing Nucleosomes with Concomitant Release of UV-damaged DNA-binding Protein E3 Ligase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92466&geneProductId=UniProtKB:Q92466

protein-containing complex binding

1 reference

8 April 2019

Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

damaged DNA binding

Characterization of a human DNA damage binding protein implicated in xeroderma pigmentosum E

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

8 April 2019

Monoubiquitinated Histone H2A Destabilizes Photolesion-containing Nucleosomes with Concomitant Release of UV-damaged DNA-binding Protein E3 Ligase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

ubiquitin-protein transferase activity

protein-containing complex binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

1 reference

8 April 2019

Cul4B-RING E3 ubiquitin ligase complex

1 reference

8 April 2019

Monoubiquitinated Histone H2A Destabilizes Photolesion-containing Nucleosomes with Concomitant Release of UV-damaged DNA-binding Protein E3 Ligase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

protein-containing complex

1 reference

8 April 2019

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

nucleoplasm

Cul4B-RING E3 ubiquitin ligase complex

3 references

protein-containing complex

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

nucleotide-excision repair

biological process

1 reference

8 April 2019

Characterization of a human DNA damage binding protein implicated in xeroderma pigmentosum E

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

pyrimidine dimer repair

Ensembl genome database project

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

nucleotide-excision repair, DNA damage recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

1 reference

8 April 2019

histone H2A monoubiquitination

1 reference

8 April 2019

Monoubiquitinated Histone H2A Destabilizes Photolesion-containing Nucleosomes with Concomitant Release of UV-damaged DNA-binding Protein E3 Ligase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

protein polyubiquitination

1 reference

8 April 2019

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

cellular response to DNA damage stimulus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

1 reference

8 April 2019

global genome nucleotide-excision repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

1 reference

8 April 2019

protein ubiquitination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

1 reference

8 April 2019

nucleotide-excision repair, DNA incision

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

1 reference

8 April 2019

UV-damage excision repair

1 reference

8 April 2019

Monoubiquitinated Histone H2A Destabilizes Photolesion-containing Nucleosomes with Concomitant Release of UV-damaged DNA-binding Protein E3 Ligase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

response to UV

1 reference

24 April 2018

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92466&geneProductId=UniProtKB:Q92466

DNA repair

protein autoubiquitination

3 references

1 reference

8 April 2019

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

nucleotide-excision repair, DNA incision, 5'-to lesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

1 reference

8 April 2019

nucleotide-excision repair, preincision complex stabilization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

1 reference

8 April 2019

nucleotide-excision repair, preincision complex assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

1 reference

8 April 2019

protein deubiquitination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

1 reference

8 April 2019

post-translational protein modification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

1 reference

8 April 2019

protein polyubiquitination

response to UV

response to UV-B

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

histone H2A monoubiquitination

protein autoubiquitination

UV-damage excision repair

nucleotide-excision repair, DNA duplex unwinding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

1 reference

8 April 2019

nucleotide-excision repair, DNA incision, 3'-to lesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

1 reference

8 April 2019

DNA repair

Mutations specific to the xeroderma pigmentosum group E Ddb- phenotype

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92466

1 reference

WD40 repeat, conserved site

1 reference

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016