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Phosphodiesterase 6C
mammalian protein found in Homo sapiens
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
cGMP phosphodiesterase 6C
cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P51160
part of
3'5'-cyclic nucleotide phosphodiesterase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P51160
3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P51160
GAF-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P51160
3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
HD/PDEase domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
GAF domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
3'5'-cyclic nucleotide phosphodiesterase, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P51160
encoded by
PDE6C
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P51160
molecular function
phosphoric diester hydrolase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
nucleotide binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51160
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
cGMP binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51160
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
3',5'-cyclic-GMP phosphodiesterase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51160
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
hydrolase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51160
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
3',5'-cyclic-nucleotide phosphodiesterase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51160
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
cell component
plasma membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51160
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51160
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
biological process
sensory perception of light stimulus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
retinal cone cell development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
visual perception
determination method
IEA
TAS
3 references
retrieved
27 March 2018
stated in
Human cone-specific cGMP phosphodiesterase alpha' subunit: complete cDNA sequence and gene arrangement
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51160&geneProductId=UniProtKB:P51160
determination method
TAS
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P51160
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51160&geneProductId=UniProtKB:P51160
determination method
IEA
retrieved
27 March 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51160&geneProductId=UniProtKB:P51160
determination method
IEA
phototransduction, visible light
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
response to stimulus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51160
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
visual perception
determination method
IBA
IEA
TAS
4 references
retrieved
8 April 2019
stated in
Human cone-specific cGMP phosphodiesterase alpha' subunit: complete cDNA sequence and gene arrangement
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51160
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51160
determination method
IBA
physically interacts with
Sildenafil
has use
enzyme inhibitor
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
4743
language of work or name
English
retrieved
17 August 2016
has part(s)
3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P51160
GAF domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P51160
HD/PDEase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P51160
3'5'-cyclic nucleotide phosphodiesterase, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P51160
Identifiers
RefSeq protein ID
NP_006195
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
5146
UniProt protein ID
P51160
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P51160
Ensembl protein ID
ENSP00000360502
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000360502
PDB structure ID
3JWQ
1 reference
stated in
UniProt
UniProt protein ID
P51160
retrieved
4 August 2016
language of work or name
English
3JWR
1 reference
stated in
UniProt
UniProt protein ID
P51160
retrieved
4 August 2016
language of work or name
English
5E8F
1 reference
stated in
UniProt
UniProt protein ID
P51160
retrieved
4 August 2016
language of work or name
English
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