(Q21124031)

http://www.ebi.ac.uk/interpro/protein/P59046

P-loop containing nucleoside triphosphate hydrolase

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P59046

Leucine-rich repeat domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P59046

NACHT-associated domain, protein family

1 reference

NACHT nucleoside triphosphatase family

1 reference

DAPIN domain, protein family

1 reference

Leucine-rich repeat, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

cysteine-type endopeptidase activator activity involved in apoptotic process

1 reference

8 April 2019

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

4 references

8 April 2019

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

8 April 2019

Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

8 April 2019

The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

8 April 2019

Evaluation of Nod-like receptor (NLR) effector domain interactions

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

8 April 2019

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

8 April 2019

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

1 reference

8 April 2019

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

biological process

dendritic cell migration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

regulation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

27 March 2018

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

http://www.ebi.ac.uk/QuickGO/annotations?protein=P59046&geneProductId=UniProtKB:P59046

regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

8 April 2019

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

activation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

8 April 2019

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

negative regulation of Toll signaling pathway

NAS

1 reference

8 April 2019

The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

1 reference

8 April 2019

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

negative regulation of NIK/NF-kappaB signaling

NAS

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

negative regulation of inflammatory response

1 reference

1 January 2018

Mutations in NALP12 cause hereditary periodic fever syndromes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

cellular response to cytokine stimulus

IMP

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P59046&geneProductId=UniProtKB:P59046

negative regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

27 March 2018

The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals

http://www.ebi.ac.uk/QuickGO/annotations?protein=P59046&geneProductId=UniProtKB:P59046

positive regulation of inflammatory response

1 reference

8 April 2019

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

negative regulation of protein autophosphorylation

NAS

1 reference

8 April 2019

The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

positive regulation of MHC class I biosynthetic process

1 reference

27 March 2018

Cutting edge: Monarch-1: a pyrin/nucleotide-binding domain/leucine-rich repeat protein that controls classical and nonclassical MHC class I genes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P59046&geneProductId=UniProtKB:P59046

negative regulation of ERK1 and ERK2 cascade

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

negative regulation of NF-kappaB transcription factor activity

1 reference

8 April 2019

Mutations in NALP12 cause hereditary periodic fever syndromes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

negative regulation of signal transduction

1 reference

8 April 2019

The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

positive regulation of NIK/NF-kappaB signaling

1 reference

8 April 2019

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P59046

negative regulation of I-kappaB kinase/NF-kappaB signaling

IBA

regulation of cysteine-type endopeptidase activity involved in apoptotic process

IBA

positive regulation of MHC class I biosynthetic process

IBA