(Q21124648)

English

Troponin I2, fast skeletal type

mammalian protein found in Homo sapiens

troponin I fast twitch 2
troponin I, fast-twitch isoform
troponin I, skeletal, fast
troponin I, fast skeletal muscle
TNNI2
troponin I, fast-twitch skeletal muscle isoform
troponin I type 2 (skeletal, fast)

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Statements

1 reference

16 January 2019

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P48788

Troponin domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P48788

1 reference

16 January 2019

1 reference

16 January 2019

1 reference

8 April 2019

Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48788

1 reference

8 April 2019

Fast skeletal muscle troponin I is a co-activator of estrogen receptor-related receptor alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48788

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48788

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48788&geneProductId=UniProtKB:P48788

27 March 2018

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48788&geneProductId=UniProtKB:P48788

27 March 2018

Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48788&geneProductId=UniProtKB:P48788

1 reference

8 April 2019

Fast skeletal muscle troponin I is a co-activator of estrogen receptor-related receptor alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48788

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48788

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48788

8 April 2019

Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48788

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48788

determination method

IBA

biological process

regulation of muscle contraction

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48788

determination method

IEA

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

Fast skeletal muscle troponin I is a co-activator of estrogen receptor-related receptor alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48788

determination method

IDA

skeletal muscle contraction

1 reference

27 March 2018

Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48788&geneProductId=UniProtKB:P48788

determination method

IDA

cardiac muscle contraction

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48788

determination method

IBA

muscle filament sliding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48788

determination method

TAS

skeletal muscle contraction

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48788

determination method

IBA

physically interacts with

tirasemtiv

object of statement has role

activation

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL3039529

Identifiers

1 reference

16 November 2018

1 reference

16 November 2018

1 reference

16 November 2018

1 reference

16 January 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

21 March 2016

language of work or name

English

(Q21124648)

Troponin I2, fast skeletal type

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Identifiers

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