(Q21126575)

English

Transmembrane protein 129, E3 ubiquitin ligase

mammalian protein found in Homo sapiens

TMEM129
E3 ubiquitin-protein ligase TM129
RING-type E3 ubiquitin transferase TM129
transmembrane protein 129, E3 ubiquitin protein ligase

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Statements

1 reference

13 November 2019

E3 ubiquitin-protein ligase TM129

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/A0AVI4

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

determination method

IEA

ubiquitin protein ligase activity

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A0AVI4&geneProductId=UniProtKB:A0AVI4

27 March 2018

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=A0AVI4&geneProductId=UniProtKB:A0AVI4

27 March 2018

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

http://www.ebi.ac.uk/QuickGO/annotations?protein=A0AVI4&geneProductId=UniProtKB:A0AVI4

27 March 2018

TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.

http://www.ebi.ac.uk/QuickGO/annotations?protein=A0AVI4&geneProductId=UniProtKB:A0AVI4

determination method

EXP

ubiquitin protein ligase activity

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

8 April 2019

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

8 April 2019

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

8 April 2019

TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

determination method

IEA

endoplasmic reticulum

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

8 April 2019

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

determination method

IBA

biological process

response to unfolded protein

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

determination method

IEA

retrograde protein transport, ER to cytosol

1 reference

8 April 2019

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

determination method

IMP

protein polyubiquitination

1 reference

8 April 2019

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

determination method

IDA

ubiquitin-dependent ERAD pathway

1 reference

8 April 2019

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0AVI4

determination method

IMP

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

(Q21126575)

Transmembrane protein 129, E3 ubiquitin ligase

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