Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q21127088)
Watch
English
Ring finger protein 125
mammalian protein found in Homo sapiens
T-cell RING activation protein 1
ring finger protein 125, E3 ubiquitin protein ligase
E3 ubiquitin-protein ligase RNF125
RNF125
RING finger protein 125
T-cell ring protein identified in activation screen
TRAC-1
In more languages
default values for all languages
No label defined
No description defined
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96EQ8
part of
Zinc finger, RING/FYVE/PHD-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q96EQ8
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
Zinc finger, RING-type, protein family
1 reference
based on heuristic
inferred from protein domain or family
Drought induced 19 protein type, zinc-binding domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Zinc finger C2HC RNF-type, protein family
1 reference
based on heuristic
inferred from protein domain or family
Zinc finger, RING-type, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96EQ8
encoded by
RNF125
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96EQ8
molecular function
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IEA
p53 binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
RNF125 is a ubiquitin-protein ligase that promotes p53 degradation
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IPI
protein binding
determination method
IPI
4 references
retrieved
8 April 2019
stated in
A non-canonical role of the p97 complex in RIG-I antiviral signaling
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IPI
retrieved
8 April 2019
stated in
Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IPI
retrieved
8 April 2019
stated in
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IPI
retrieved
8 April 2019
stated in
Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IPI
transferase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IEA
zinc ion binding
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IDA
ubiquitin conjugating enzyme binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IPI
ubiquitin protein ligase activity
determination method
IDA
3 references
retrieved
8 April 2019
stated in
RNF125 is a ubiquitin-protein ligase that promotes p53 degradation
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IDA
retrieved
8 April 2019
stated in
A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IDA
retrieved
8 April 2019
stated in
Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IDA
cell component
intracellular membrane-bounded organelle
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IDA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IEA
Golgi membrane
determination method
IEA
IDA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IEA
retrieved
8 April 2019
stated in
T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IDA
Golgi apparatus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IEA
VCP-NPL4-UFD1 AAA ATPase complex
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
A non-canonical role of the p97 complex in RIG-I antiviral signaling
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IDA
biological process
adaptive immune response
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IEA
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
determination method
IBA
1 reference
retrieved
27 February 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96EQ8&geneProductId=UniProtKB:Q96EQ8
determination method
IBA
protein ubiquitination
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IEA
immune system process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IEA
ubiquitin-dependent protein catabolic process
determination method
IDA
2 references
retrieved
8 April 2019
stated in
A non-canonical role of the p97 complex in RIG-I antiviral signaling
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IDA
retrieved
8 April 2019
stated in
Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IDA
negative regulation of type I interferon production
determination method
IDA
2 references
retrieved
8 April 2019
stated in
A non-canonical role of the p97 complex in RIG-I antiviral signaling
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IDA
retrieved
8 April 2019
stated in
Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IDA
negative regulation of RIG-I signaling pathway
determination method
IDA
2 references
retrieved
8 April 2019
stated in
A non-canonical role of the p97 complex in RIG-I antiviral signaling
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IDA
retrieved
8 April 2019
stated in
Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IDA
protein polyubiquitination
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125
GOA
curator
UniProt
UniProt protein ID
Q96EQ8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96EQ8
determination method
IDA
has part(s)
Zinc finger, RING-type, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q96EQ8
Drought induced 19 protein type, zinc-binding domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q96EQ8
Zinc finger, RING-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q96EQ8
Zinc finger C2HC RNF-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q96EQ8
Identifiers
RefSeq protein ID
NP_060301
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
54941
XP_011524347
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
54941
XP_011524348
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
54941
XP_011524349
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
54941
UniProt protein ID
Q96EQ8
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96EQ8
Ensembl protein ID
ENSP00000217740
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000217740
ENSP00000463935
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000463935
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit