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Cas scaffold protein family member 4
mammalian protein found in Homo sapiens
HEF-like protein
HEF1-EFS-p130Cas-like protein
CASS4
HEPL
cas scaffolding protein family member 4
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9NQ75
part of
Cas scaffolding protein family member 4
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NQ75
SH3-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NQ75
CAS, serine rich four helix bundle domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NQ75
Cas scaffolding protein family member 4, SH3 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Serine rich protein interaction domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
CAS family, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
SH3 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9NQ75
encoded by
CASS4
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9NQ75
molecular function
structural constituent of cytoskeleton
determination method
IEA
1 reference
retrieved
14 March 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q9NQ75
determination method
IEA
protein tyrosine kinase binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
A novel Cas family member, HEPL, regulates FAK and cell spreading
GOA
curator
UniProt
UniProt protein ID
Q9NQ75
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQ75
determination method
IPI
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NQ75
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQ75&geneProductId=UniProtKB:Q9NQ75
determination method
IEA
cell junction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NQ75
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQ75
determination method
IEA
cytoskeleton
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NQ75
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQ75
determination method
IEA
focal adhesion
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NQ75
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQ75&geneProductId=UniProtKB:Q9NQ75
determination method
IEA
focal adhesion
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NQ75
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQ75
determination method
IEA
retrieved
8 April 2019
stated in
A novel Cas family member, HEPL, regulates FAK and cell spreading
GOA
curator
UniProt
UniProt protein ID
Q9NQ75
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQ75
determination method
IDA
cytoplasm
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NQ75
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQ75
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQ75
determination method
IBA
plasma membrane
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQ75
determination method
IBA
biological process
cell adhesion
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NQ75
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQ75
determination method
IEA
positive regulation of cell migration
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
A novel Cas family member, HEPL, regulates FAK and cell spreading
GOA
curator
UniProt
UniProt protein ID
Q9NQ75
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQ75
determination method
IMP
positive regulation of protein tyrosine kinase activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
A novel Cas family member, HEPL, regulates FAK and cell spreading
GOA
curator
UniProt
UniProt protein ID
Q9NQ75
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQ75
determination method
IDA
positive regulation of substrate adhesion-dependent cell spreading
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
A novel Cas family member, HEPL, regulates FAK and cell spreading
GOA
curator
UniProt
UniProt protein ID
Q9NQ75
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQ75
determination method
IMP
cell migration
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQ75
determination method
IBA
actin filament reorganization
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQ75
determination method
IBA
has part(s)
CAS family, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NQ75
Serine rich protein interaction domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NQ75
SH3 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NQ75
Cas scaffolding protein family member 4, SH3 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NQ75
Identifiers
RefSeq protein ID
NP_001157586
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57091
NP_001157587
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57091
NP_001157588
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57091
NP_065089
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57091
XP_006723894
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57091
UniProt protein ID
Q9NQ75
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9NQ75
Ensembl protein ID
ENSP00000353462
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000353462
ENSP00000410027
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000410027
PDB structure ID
2CRE
1 reference
stated in
UniProt
UniProt protein ID
Q9NQ75
retrieved
9 August 2016
language of work or name
English
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