(Q21132717)

English

Protein phosphatase 2 regulatory subunit B'alpha

mammalian protein found in Homo sapiens

PR61alpha
protein phosphatase 2 regulatory subunit B', alpha
PP2A B subunit isoform R5-alpha
PP2A B subunit isoform PR61-alpha
protein phosphatase 2, regulatory subunit B (B56), alpha isoform
PP2A, B subunit, R5 alpha isoform
PP2A, B subunit, B56 alpha isoform
serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform
PP2A, B subunit, B' alpha isoform
PP2A B subunit isoform B56-alpha
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha isoform
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
PP2A, B subunit, PR61 alpha isoform
PP2A B subunit isoform B'-alpha

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

Armadillo-like helical

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15172

Protein phosphatase 2A, regulatory B subunit, B56

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15172

Armadillo-type fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15172

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method

1 reference

8 April 2019

A critical role for the protein phosphatase 2A B'α regulatory subunit in dephosphorylation of sphingosine kinase 1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

protein binding

determination method

12 references

8 April 2019

Bod1 regulates protein phosphatase 2A at mitotic kinetochores

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

Binding specificity of protein phosphatase 2A core enzyme for regulatory B subunits and T antigens

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

Regulation of Chk2 phosphorylation by interaction with protein phosphatase 2A via its B' regulatory subunit

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

Screening and identification of proteins interacting with nucleostemin

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

Shugoshin collaborates with protein phosphatase 2A to protect cohesin

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

The tumor suppressor PP2A Abeta regulates the RalA GTPase

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

Identification of a new family of protein phosphatase 2A regulatory subunits

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

phosphoprotein phosphatase activity

determination method

1 reference

8 April 2019

Bod1 regulates protein phosphatase 2A at mitotic kinetochores

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

protein phosphatase activator activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

determination method

3 references

8 April 2019

The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

A critical role for the protein phosphatase 2A B'α regulatory subunit in dephosphorylation of sphingosine kinase 1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

chromosome, centromeric region

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

determination method

1 reference

8 April 2019

D1 dopamine receptor signaling involves caveolin-2 in HEK-293 cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

determination method

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15172&geneProductId=UniProtKB:Q15172

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

determination method

1 reference

16 July 2018

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15172&geneProductId=UniProtKB:Q15172

determination method

determination method

1 reference

8 April 2019

Bod1 regulates protein phosphatase 2A at mitotic kinetochores

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

protein phosphatase type 2A complex

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

biological process

negative regulation of lipid kinase activity

determination method

1 reference

8 April 2019

A critical role for the protein phosphatase 2A B'α regulatory subunit in dephosphorylation of sphingosine kinase 1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

positive regulation of protein dephosphorylation

determination method

1 reference

8 April 2019

A critical role for the protein phosphatase 2A B'α regulatory subunit in dephosphorylation of sphingosine kinase 1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

signal transduction

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

negative regulation of protein localization to plasma membrane

determination method

1 reference

8 April 2019

A critical role for the protein phosphatase 2A B'α regulatory subunit in dephosphorylation of sphingosine kinase 1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

protein dephosphorylation

determination method

1 reference

10 September 2018

Bod1 regulates protein phosphatase 2A at mitotic kinetochores

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15172&geneProductId=UniProtKB:Q15172

determination method

regulation of phosphoprotein phosphatase activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

regulation of protein autophosphorylation

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15172

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000261461

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000261461

ENSP00000442866

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000442866

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Multilingual sites(0 entries)

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