(Q21133440)

cytochrome b5-like heme/steroid binding domain superfamily

1 reference

Ribosomal protein L2, domain 2

1 reference

Galactose-binding-like domain superfamily

1 reference

Mib/herc2 domain superfamily

1 reference

Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II

1 reference

Zinc finger, ZZ-type, protein family

1 reference

CPH domain, protein family

1 reference

HECT domain, protein family

1 reference

cytochrome b5-like heme/steroid binding domain, protein family

1 reference

APC10/DOC domain, protein family

1 reference

HERC2, APC10 domain, protein family

1 reference

Mib-herc2 domain, protein family

1 reference

Regulator of chromosome condensation, RCC1, protein family

1 reference

Beta-propeller repeat TECPR, protein family

1 reference

guanyl-nucleotide exchange factor activity

image

Protein HERC2 PDB 2KEO.png
1,200 × 1,000; 135 KB

1 reference

PDB structure ID

2KEO

HERC2.png
1,920 × 975; 735 KB

0 references

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

The ancestral gene for transcribed, low-copy repeats in the Prader-Willi/Angelman region encodes a large protein implicated in protein trafficking, which is deficient in mice with neuromuscular and spermiogenic abnormalities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

1 reference

8 April 2019

DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

4 references

8 April 2019

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

8 April 2019

Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

8 April 2019

Network analysis of UBE3A/E6AP-associated proteins provides connections to several distinct cellular processes.

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

8 April 2019

Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

ubiquitin protein ligase binding

IPI

1 reference

8 April 2019

DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

ubiquitin protein ligase activity

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95714&geneProductId=UniProtKB:O95714

1 reference

31 October 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95714&geneProductId=UniProtKB:O95714

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

mitochondrial inner membrane

TAS

1 reference

31 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95714&geneProductId=UniProtKB:O95714

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

8 April 2019

Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

1 reference

8 April 2019

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

HDA

biological process

protein ubiquitination

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

8 April 2019

Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

intracellular protein transport

1 reference

8 April 2019

The ancestral gene for transcribed, low-copy repeats in the Prader-Willi/Angelman region encodes a large protein implicated in protein trafficking, which is deficient in mice with neuromuscular and spermiogenic abnormalities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

double-strand break repair via nonhomologous end joining

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

proteasome-mediated ubiquitin-dependent protein catabolic process

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95714&geneProductId=UniProtKB:O95714

regulation of molecular function

IBA

1 reference

31 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95714&geneProductId=UniProtKB:O95714

cellular response to DNA damage stimulus

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

8 April 2019

DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95714

1 reference

APC10/DOC domain

1 reference

CPH domain

1 reference

Zinc finger, ZZ-type

1 reference

HECT domain

1 reference

Beta-propeller repeat TECPR

1 reference

cytochrome b5-like heme/steroid binding domain

1 reference

Regulator of chromosome condensation, RCC1

1 reference

HERC2, APC10 domain

1 reference