(Q21134412)

Immunoglobulin-like fold

1 reference

LDL receptor-like superfamily

1 reference

Six-bladed beta-propeller, TolB-like

1 reference

WD40/YVTN repeat-like-containing domain superfamily

1 reference

Putative uncharacterized transport proteins

1 reference

Transporter Classification Database ID

9.B.87.1.17

retrieved

2 October 2019

hierarchical database ID heuristic

membrane proteins

1 reference

inferred from GOA cell component → membrane

VPS10, protein family

1 reference

Sortilin, C-terminal domain, protein family

1 reference

Fibronectin type III, protein family

1 reference

Sortilin, N-terminal domain, protein family

1 reference

Low-density lipoprotein (LDL) receptor class A, conserved site, protein family

1 reference

Low-density lipoprotein (LDL) receptor class A repeat, protein family

1 reference

LDLR class B repeat, protein family

1 reference

low-density lipoprotein particle binding

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

3 January 2017

Apolipoprotein A-V interaction with members of the low density lipoprotein receptor gene family

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

5 references

3 January 2017

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

LR11, an LDL receptor gene family member, is a novel regulator of smooth muscle cell migration

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

SORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processes

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

transmembrane signaling receptor activity

IPI

1 reference

3 January 2017

A novel mosaic protein containing LDL receptor elements is highly conserved in humans and chickens

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

integral component of membrane

TAS

cell component

2 references

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

1 reference

3 January 2017

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

1 reference

3 January 2017

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

integral component of plasma membrane

1 reference

3 January 2017

A novel mosaic protein containing LDL receptor elements is highly conserved in humans and chickens

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

1 reference

3 January 2017

SORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processes

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

endoplasmic reticulum

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

low-density lipoprotein particle

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

nuclear envelope lumen

3 references

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

1 reference

3 January 2017

LR11, an LDL receptor gene family member, is a novel regulator of smooth muscle cell migration

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

steroid metabolic process

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

protein targeting to lysosome

1 reference

3 January 2017

Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

positive regulation of protein catabolic process

1 reference

3 January 2017

Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

negative regulation of amyloid-beta formation

7 references

3 January 2017

Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

SORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processes

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

negative regulation of protein oligomerization

1 reference

3 January 2017

Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

1 reference

3 January 2017

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

4 references

3 January 2017

Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

cholesterol metabolic process

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

negative regulation of protein binding

1 reference

3 January 2017

Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

positive regulation of ER to Golgi vesicle-mediated transport

1 reference

3 January 2017

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

receptor-mediated endocytosis

IMP

1 reference

3 January 2017

A novel mosaic protein containing LDL receptor elements is highly conserved in humans and chickens

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

positive regulation of early endosome to recycling endosome transport

TAS

1 reference

3 January 2017

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

post-Golgi vesicle-mediated transport

IMP

1 reference

3 January 2017

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

positive regulation of endocytic recycling

1 reference

3 January 2017

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

regulation of smooth muscle cell migration

IMP

1 reference

3 January 2017

LR11, an LDL receptor gene family member, is a novel regulator of smooth muscle cell migration

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

positive regulation of protein localization to early endosome

1 reference

3 January 2017

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process

3 references

3 January 2017

Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

positive regulation of protein exit from endoplasmic reticulum

1 reference

3 January 2017

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

1 reference

3 January 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q92673

Low-density lipoprotein (LDL) receptor class A, conserved site

has part(s)

1 reference

fibronectin type III

1 reference

Sortilin, C-terminal

1 reference

VPS10

1 reference

low-density lipoprotein (LDL) receptor class A repeat

1 reference

Sortilin, N-terminal

1 reference

LDLR class B repeat

1 reference

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

Transporter Classification Database ID

English

9.B.87.1.17

2 references

Transporter Classification database

retrieved

13 March 2020