Wikidata

(Q21135798)

English

TNF receptor superfamily member 10b

mammalian protein found in Homo sapiens

  • TRAIL receptor 2
  • cytotoxic TRAIL receptor-2
  • p53-regulated DNA damage-inducible cell death receptor(killer)
  • tumor necrosis factor receptor-like protein ZTNFR9
  • TNFRSF10B
  • TNF-related apoptosis-inducing ligand receptor 2
  • tumor necrosis factor receptor superfamily member 10B
  • death domain containing receptor for TRAIL/Apo-2L
  • Fas-like protein
  • death receptor 5
  • TRAIL-R2
  • tumor necrosis factor receptor superfamily, member 10b
  • apoptosis inducing protein TRICK2A/2B
  • apoptosis inducing receptor TRAIL-R2
In more languages

Statements

molecular function
protein binding
determination method
IPI
9 references
retrieved
8 April 2019
stated in
Inhibition of vacuolar ATPase attenuates the TRAIL-induced activation of caspase-8 and modulates the trafficking of TRAIL receptosomes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14763
determination method
IPI
retrieved
8 April 2019
stated in
Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14763
determination method
IPI
retrieved
8 April 2019
stated in
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14763
determination method
IPI
retrieved
8 April 2019
stated in
Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14763
determination method
IPI
retrieved
8 April 2019
stated in
Identification of a novel pro-apoptotic role of NF-κB in the regulation of TRAIL- and CD95-mediated apoptosis of glioblastoma cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14763
determination method
IPI
retrieved
8 April 2019
stated in
Identification of a novel proapoptotic function of resveratrol in fat cells: SIRT1-independent sensitization to TRAIL-induced apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14763
determination method
IPI
retrieved
8 April 2019
stated in
Bortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14763
determination method
IPI
retrieved
8 April 2019
stated in
Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14763
determination method
IPI
retrieved
8 April 2019
stated in
Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14763
determination method
IPI
cell component
biological process

Identifiers

 
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