Wikidata

(Q21136120)

English

TERF2 interacting protein

mammalian protein found in Homo sapiens

  • RAP1 homolog
  • dopamine receptor-interacting protein 5
  • TRF2-interacting telomeric RAP1 protein
  • TERF2IP
  • repressor/activator protein 1 homolog
  • hRap1
  • TERF2-interacting telomeric protein 1
  • telomeric repeat-binding factor 2-interacting protein 1
In more languages

Statements

molecular function
protein binding
determination method
IPI
16 references
retrieved
8 April 2019
stated in
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair
GOA
curator
UniProt
UniProt protein ID
Q9NYB0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes
GOA
curator
UniProt
UniProt protein ID
Q9NYB0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
Human UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replication
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
NEDD8 ultimate buster-1 regulates the abundance of TRF1 at telomeres by promoting its proteasomal degradation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
POT1 association with TRF2 regulates telomere length
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
PTOP interacts with POT1 and regulates its localization to telomeres
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
TRF2 interaction with Ku heterotetramerization interface gives insight into c-NHEJ prevention at human telomeres
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
8 April 2019
stated in
TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
protein binding
determination method
IBA
IPI
17 references
retrieved
1 January 2018
stated in
ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes
GOA
curator
UniProt
UniProt protein ID
Q9NYB0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair
GOA
curator
UniProt
UniProt protein ID
Q9NYB0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
NEDD8 ultimate buster-1 regulates the abundance of TRF1 at telomeres by promoting its proteasomal degradation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
Human UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replication
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
POT1 association with TRF2 regulates telomere length
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
TRF2 interaction with Ku heterotetramerization interface gives insight into c-NHEJ prevention at human telomeres
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
PTOP interacts with POT1 and regulates its localization to telomeres
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IPI
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NYB0
determination method
IBA
cell component
biological process

Identifiers

 
edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21136120&oldid=2023027643"