Wikidata

(Q21170876)

English

TATA-box binding protein associated factor 1

mammalian protein found in Homo sapiens

  • TAFII250
  • cell cycle gene 1 protein
  • TBP-associated factor 250 kDa
  • transcription initiation factor TFIID subunit 1
  • transcription factor TFIID p250 polypeptide
  • Transcription initiation factor TFIID 250 kDa subunit
  • TAFII-250
  • TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
  • TAF1
  • p250
  • cell cycle, G1 phase defect
  • complementation of cell cycle block, G1-to-S
  • TAF(II)250
In more languages

Statements

molecular function
protein binding
determination method
IPI
17 references
retrieved
8 April 2019
stated in
Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators
GOA
curator
UniProt
UniProt protein ID
P21675
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation
GOA
curator
UniProt
UniProt protein ID
P21675
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
Evolutionary conservation of human TATA-binding-polypeptide-associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors
GOA
curator
UniProt
UniProt protein ID
P21675
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
Rb inhibits the intrinsic kinase activity of TATA-binding protein-associated factor TAFII250
GOA
curator
UniProt
UniProt protein ID
P21675
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID
GOA
curator
UniProt
UniProt protein ID
P21675
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
The crystal structure of CCG1/TAF(II)250-interacting factor B (CIB)
GOA
curator
UniProt
UniProt protein ID
P21675
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation
GOA
curator
UniProt
UniProt protein ID
P21675
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
The cell cycle regulatory factor TAF1 stimulates ribosomal DNA transcription by binding to the activator UBF
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
TAF1 differentially enhances androgen receptor transcriptional activity via its N-terminal kinase and ubiquitin-activating and -conjugating domains
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
Transcription factor TAFII250 phosphorylates the acidic domain of Mdm2 through recruitment of protein kinase CK2
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
Function of TAF(II)-containing complex without TBP in transcription by RNA polymerase II
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
Histone-like TAFs within the PCAF histone acetylase complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
retrieved
8 April 2019
stated in
Subregions of the adenovirus E1A transactivation domain target multiple components of the TFIID complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IPI
cell component
transcription factor TFIID complex
determination method
IDA
IEA
TAS
7 references
retrieved
24 April 2018
stated in
Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21675&geneProductId=UniProtKB:P21675
determination method
TAS
retrieved
24 April 2018
stated in
The cell cycle regulatory factor TAF1 stimulates ribosomal DNA transcription by binding to the activator UBF
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21675&geneProductId=UniProtKB:P21675
determination method
TAS
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21675&geneProductId=UniProtKB:P21675
determination method
IEA
retrieved
24 April 2018
stated in
Structure of promoter-bound TFIID and model of human pre-initiation complex assembly
GOA
curator
UniProt
UniProt protein ID
P21675
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21675&geneProductId=UniProtKB:P21675
determination method
IDA
retrieved
24 April 2018
stated in
Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21675&geneProductId=UniProtKB:P21675
determination method
IDA
retrieved
24 April 2018
stated in
The TBN Protein, which Is Essential for Early Embryonic Mouse Development, Is an Inducible TAFII Implicated In Adipogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21675&geneProductId=UniProtKB:P21675
determination method
IDA
retrieved
24 April 2018
stated in
TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P21675&geneProductId=UniProtKB:P21675
determination method
IDA
transcription factor TFIID complex
determination method
IBA
IDA
IEA
TAS
8 references
retrieved
8 April 2019
stated in
The cell cycle regulatory factor TAF1 stimulates ribosomal DNA transcription by binding to the activator UBF
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
TAS
retrieved
8 April 2019
stated in
Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IEA
retrieved
8 April 2019
stated in
Structure of promoter-bound TFIID and model of human pre-initiation complex assembly
GOA
curator
UniProt
UniProt protein ID
P21675
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IDA
retrieved
8 April 2019
stated in
Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IDA
retrieved
8 April 2019
stated in
The TBN Protein, which Is Essential for Early Embryonic Mouse Development, Is an Inducible TAFII Implicated In Adipogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IDA
retrieved
8 April 2019
stated in
TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21675
determination method
IBA
biological process

Identifiers

 
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