(Q21174843)

http://www.ebi.ac.uk/interpro/protein/O60907

Quinoprotein alcohol dehydrogenase-like superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O60907

WD40-repeat-containing domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O60907

LIS1 homology motif, protein family

1 reference

WD40 repeat, protein family

1 reference

WD40 repeat, conserved site, protein family

1 reference

G-protein beta WD-40 repeat, protein family

1 reference

TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

transcription corepressor activity

protein domain specific binding

IGI

1 reference

8 April 2019

A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

1 reference

8 April 2019

Reading and function of a histone code involved in targeting corepressor complexes for repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

transcription factor binding

1 reference

8 April 2019

TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

protein C-terminus binding

1 reference

8 April 2019

TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

3 references

8 April 2019

Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

8 April 2019

The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

8 April 2019

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

identical protein binding

1 reference

27 March 2018

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60907&geneProductId=UniProtKB:O60907

transcription corepressor activity

3 references

8 April 2019

Reading and function of a histone code involved in targeting corepressor complexes for repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

8 April 2019

Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

histone deacetylase complex

IBA

cell component

1 reference

27 March 2018

Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachment

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60907&geneProductId=UniProtKB:O60907

transcription repressor complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

1 reference

27 March 2018

Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachment

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60907&geneProductId=UniProtKB:O60907

1 reference

8 April 2019

Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

regulation of transcription, DNA-templated

biological process

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60907&geneProductId=UniProtKB:O60907

negative regulation of transcription by RNA polymerase II

IEA

1 reference

8 April 2019

Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

sensory perception of sound

1 reference

8 April 2019

X-linked late-onset sensorineural deafness caused by a deletion involving OA1 and a novel gene containing WD-40 repeats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

transcription, DNA-templated

IMP

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O60907&geneProductId=UniProtKB:O60907

1 reference

8 April 2019

TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

positive regulation of transcription, DNA-templated

IMP

1 reference

8 April 2019

TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

histone deacetylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

positive regulation of transcription by RNA polymerase II

IBA

1 reference

8 April 2019

TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

proteasome-mediated ubiquitin-dependent protein catabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

regulation of lipid metabolic process

ISS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

positive regulation of canonical Wnt signaling pathway

TAS

1 reference

8 April 2019

TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907

IMP

protein stabilization

1 reference

8 April 2019

regulation of transcription by RNA polymerase II

ISS

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60907