(Q21204197)

http://www.ebi.ac.uk/interpro/protein/P98082

membrane proteins

1 reference

based on heuristic

inferred from GOA cell component → membrane

PTB/PI domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

clathrin adaptor activity

1 reference

9 May 2019

The adaptor protein Dab2 sorts LDL receptors into coated pits independently of AP-2 and ARH

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

protein C-terminus binding

1 reference

9 May 2019

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

7 references

9 May 2019

Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

9 May 2019

Disabled-2 (Dab2) inhibits Wnt/β-catenin signalling by binding LRP6 and promoting its internalization through clathrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

9 May 2019

Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

9 May 2019

A human MAP kinase interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

9 May 2019

The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

9 May 2019

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

9 May 2019

Regulation of the Wnt signaling pathway by disabled-2 (Dab2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

The adaptor protein Dab2 sorts LDL receptors into coated pits independently of AP-2 and ARH

IPI

cargo receptor activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

1 reference

9 May 2019

The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

intracellular membrane-bounded organelle

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

1 reference

17 October 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P98082&geneProductId=UniProtKB:P98082

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P98082&geneProductId=UniProtKB:P98082

clathrin-coated vesicle membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

extracellular exosome

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P98082&geneProductId=UniProtKB:P98082

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration

clathrin-coated vesicle

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

1 reference

9 May 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

positive regulation of transforming growth factor beta receptor signaling pathway

1 reference

9 May 2019

The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

positive regulation of protein phosphorylation

1 reference

9 May 2019

Regulation of the Wnt signaling pathway by disabled-2 (Dab2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

positive regulation of cell migration

1 reference

9 May 2019

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

positive regulation of pathway-restricted SMAD protein phosphorylation

1 reference

9 May 2019

The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

negative regulation of androgen receptor signaling pathway

1 reference

9 May 2019

The role of DOC-2/DAB2 in modulating androgen receptor-mediated cell growth via the nongenomic c-Src-mediated pathway in normal prostatic epithelium and cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

negative regulation of apoptotic process

1 reference

9 May 2019

Disabled-2 (Dab2) is required for transforming growth factor beta-induced epithelial to mesenchymal transition (EMT)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

Wnt signaling pathway

1 reference

9 May 2019

negative regulation of protein binding

1 reference

9 May 2019

Regulation of the Wnt signaling pathway by disabled-2 (Dab2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

positive regulation of epithelial to mesenchymal transition

1 reference

9 May 2019

Disabled-2 (Dab2) is required for transforming growth factor beta-induced epithelial to mesenchymal transition (EMT)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

leading edge cell differentiation

1 reference

9 May 2019

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

multicellular organism development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

positive regulation of transcription, DNA-templated

1 reference

9 May 2019

Regulation of the Wnt signaling pathway by disabled-2 (Dab2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

positive regulation of endocytosis

negative regulation of protein localization to plasma membrane

1 reference

9 May 2019

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

positive regulation of clathrin-dependent endocytosis

1 reference

9 May 2019

The adaptor protein Dab2 sorts LDL receptors into coated pits independently of AP-2 and ARH

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

positive regulation of early endosome to late endosome transport

1 reference

9 May 2019

Dab2 is a key regulator of endocytosis and post-endocytic trafficking of the cystic fibrosis transmembrane conductance regulator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

integrin-mediated signaling pathway

1 reference

9 May 2019

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

positive regulation of Wnt signaling pathway, planar cell polarity pathway

1 reference

9 May 2019

Regulation of the Wnt signaling pathway by disabled-2 (Dab2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

cell population proliferation

1 reference

1 January 2018

DOC-2, a candidate tumor suppressor gene in human epithelial ovarian cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

negative regulation of transcription, DNA-templated

TAS

1 reference

9 May 2019

Regulation of the Wnt signaling pathway by disabled-2 (Dab2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

1 reference

9 May 2019

Regulation of the Wnt signaling pathway by disabled-2 (Dab2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

positive regulation of SMAD protein signal transduction

1 reference

9 May 2019

The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

receptor-mediated endocytosis

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

membrane organization

1 reference

9 May 2019

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P98082&geneProductId=UniProtKB:P98082

receptor-mediated endocytosis

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

positive regulation of endocytosis

IBA

3 references

9 May 2019

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

9 May 2019

Dab2 is a key regulator of endocytosis and post-endocytic trafficking of the cystic fibrosis transmembrane conductance regulator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

negative regulation of canonical Wnt signaling pathway

IBA

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

9 May 2019

Regulation of the Wnt signaling pathway by disabled-2 (Dab2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P98082

1 reference

InterPro Release 71.0