Wikidata

(Q21493903)

English

Nuclear factor, erythroid derived 2, like 2

mammalian protein found in Mus musculus

  • nuclear factor erythroid 2-related factor 2
  • Nfe2l2
  • NF-E2-related factor 2
  • NFE2-related factor 2
In more languages

Statements

molecular function
DNA binding
determination method
IDA
IEA
ISO
7 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q60795
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
14 February 2019
stated in
Multiple basic-leucine zipper proteins regulate induction of the mouse heme oxygenase-1 gene by arsenite
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
protein binding
determination method
IPI
8 references
retrieved
14 February 2019
stated in
Cloning and characterization of the mouse polyamine-modulated factor-1 (mPMF-1) gene: an alternatively spliced homologue of the human transcription factor
GOA
curator
UniProt
UniProt protein ID
Q60795
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IPI
retrieved
14 February 2019
stated in
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IPI
retrieved
14 February 2019
stated in
Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IPI
retrieved
14 February 2019
stated in
Dihydro-CDDO-trifluoroethyl amide suppresses inflammatory responses in macrophages via activation of Nrf2
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IPI
retrieved
14 February 2019
stated in
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IPI
retrieved
14 February 2019
stated in
Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IPI
retrieved
14 February 2019
stated in
Kinetic, Thermodynamic, and Structural Characterizations of the Association between Nrf2-DLGex Degron and Keap1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IPI
retrieved
14 February 2019
stated in
Bioinformatics and cellular signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IPI
cell component
cytoplasm
determination method
IPI
IDA
IEA
ISO
8 references
retrieved
16 July 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
ISO
retrieved
16 July 2018
stated in
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IPI
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q60795
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
16 July 2018
stated in
ERRbeta: a potent inhibitor of Nrf2 transcriptional activity
GOA
curator
UniProt
UniProt protein ID
Q60795
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
16 July 2018
stated in
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
16 July 2018
stated in
CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IDA
nucleus
determination method
IDA
IEA
ISO
11 references
retrieved
16 July 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
ISO
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q60795
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
16 July 2018
stated in
ERRbeta: a potent inhibitor of Nrf2 transcriptional activity
GOA
curator
UniProt
UniProt protein ID
Q60795
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
16 July 2018
stated in
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
16 July 2018
stated in
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
16 July 2018
stated in
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
16 July 2018
stated in
Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
16 July 2018
stated in
Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
16 July 2018
stated in
Laminar flow activation of ERK5 protein in vascular endothelium leads to atheroprotective effect via NF-E2-related factor 2 (Nrf2) activation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60795&geneProductId=UniProtKB:Q60795
determination method
IDA
nucleus
determination method
IBA
IDA
IEA
ISO
12 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q60795
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
14 February 2019
stated in
ERRbeta: a potent inhibitor of Nrf2 transcriptional activity
GOA
curator
UniProt
UniProt protein ID
Q60795
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
Laminar flow activation of ERK5 protein in vascular endothelium leads to atheroprotective effect via NF-E2-related factor 2 (Nrf2) activation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IBA
cytoplasm
determination method
IBA
IDA
IEA
IPI
ISO
9 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
ISO
retrieved
14 February 2019
stated in
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IPI
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q60795
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
14 February 2019
stated in
ERRbeta: a potent inhibitor of Nrf2 transcriptional activity
GOA
curator
UniProt
UniProt protein ID
Q60795
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IBA
biological process
positive regulation of transcription by RNA polymerase II
determination method
IDA
IEA
IMP
ISO
7 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
ISO
retrieved
14 February 2019
stated in
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IEA
retrieved
14 February 2019
stated in
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
Nrf2 transcriptionally activates the mafG gene through an antioxidant response element
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA
retrieved
14 February 2019
stated in
CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60795
determination method
IDA

Identifiers

 
edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21493903&oldid=2023102625"