(Q21498359)

Armadillo-type fold

1 reference

Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily

1 reference

Phosphatidylinositol 3-/4-kinase, catalytic domain, protein family

1 reference

DNA-dependent protein kinase catalytic subunit, catalytic domain, protein family

1 reference

PIK-related kinase, FAT family

1 reference

NUC194 domain, protein family

1 reference

PIK-related kinase family

1 reference

FATC domain, protein family

1 reference

Phosphatidylinositol 3/4-kinase, conserved site, protein family

1 reference

GAPDH mediates nitrosylation of nuclear proteins

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

protein serine/threonine kinase activity

IPI

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

DNA-dependent protein kinase activity

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

double-stranded DNA binding

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

protein serine/threonine kinase activity

IDA

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

nonhomologous end joining complex

cell component

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

24 April 2018

Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

positive regulation of apoptotic process

biological process

1 reference

9 May 2019

DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

immunoglobulin V(D)J recombination

1 reference

24 April 2018

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

lymphocyte differentiation

1 reference

9 May 2019

Bcl-2 expression promotes B- but not T-lymphoid development in scid mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

1 reference

9 May 2019

p53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and Prkdc

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

regulation of smooth muscle cell proliferation

1 reference

9 May 2019

Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

regulation of circadian rhythm

IGI

1 reference

9 May 2019

Phosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period length

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

T cell lineage commitment

1 reference

9 May 2019

Distinct patterns of Fas cell surface expression during development of T- or B-lymphocyte lineages in normal, scid, and mutant mice lacking or overexpressing p53, bcl-2, or rag-2 genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

response to ionizing radiation

1 reference

9 May 2019

Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

response to gamma radiation

1 reference

9 May 2019

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

negative regulation of protein phosphorylation

1 reference

9 May 2019

Phosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period length

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

intrinsic apoptotic signaling pathway in response to DNA damage

1 reference

24 April 2018

Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

1 reference

9 May 2019

p53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and Prkdc

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

Phosphorylation and regulation of DNA ligase IV stability by DNA-dependent protein kinase

IGI

protein destabilization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

double-strand break repair

IDA

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

24 April 2018

Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

24 April 2018

Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

cellular response to DNA damage stimulus

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

pro-B cell differentiation

1 reference

9 May 2019

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

1 reference

9 May 2019

p53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and Prkdc

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

1 reference

24 April 2018

Dysfunctional mammalian telomeres join with DNA double-strand breaks

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

T cell receptor V(D)J recombination

1 reference

9 May 2019

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

ectopic germ cell programmed cell death

1 reference

9 May 2019

DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

T cell differentiation in thymus

1 reference

9 May 2019

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

B cell lineage commitment

1 reference

9 May 2019

Distinct patterns of Fas cell surface expression during development of T- or B-lymphocyte lineages in normal, scid, and mutant mice lacking or overexpressing p53, bcl-2, or rag-2 genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

immune system process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

innate immune response

1 reference

9 May 2019

double-strand break repair

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

cell population proliferation

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

regulation of epithelial cell proliferation

ISO

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P97313&geneProductId=UniProtKB:P97313

cellular response to DNA damage stimulus

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

cellular response to DNA damage stimulus

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97313

positive regulation of double-strand break repair via nonhomologous end joining

PIK-related kinase, FAT

1 reference

FATC domain

1 reference

PIK-related kinase

1 reference

Phosphatidylinositol 3-/4-kinase, catalytic domain

1 reference

Phosphatidylinositol 3/4-kinase, conserved site

1 reference

NUC194

1 reference

DNA-dependent protein kinase catalytic subunit, catalytic domain

1 reference