(Q21498562)

membrane proteins

1 reference

inferred from GOA cell component → membrane

Homeobox domain, protein family

1 reference

Homeobox engrailed, C-terminal domain, protein family

1 reference

Engrailed homeobox protein

1 reference

Homeobox domain, metazoa, protein family

1 reference

Homeobox engrailed-type, conserved site, protein family

1 reference

Homeobox, conserved site, protein family

1 reference

sequence-specific DNA binding

1 reference

25 May 2022

1 reference

25 May 2022

2 references

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09065&geneProductId=UniProtKB:P09065

DNA-binding transcription repressor activity, RNA polymerase II-specific

IEA

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09065&geneProductId=UniProtKB:P09065

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09065&geneProductId=UniProtKB:P09065

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

1 reference

14 February 2019

Specification of dopaminergic subsets involves interplay of En1 and Pitx3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

4 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09065&geneProductId=UniProtKB:P09065

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09065&geneProductId=UniProtKB:P09065

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09065&geneProductId=UniProtKB:P09065

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09065&geneProductId=UniProtKB:P09065

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

negative regulation of neuron apoptotic process

IBA

biological process

1 reference

14 February 2019

Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

dopaminergic neuron differentiation

1 reference

14 February 2019

The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

regulation of transcription, DNA-templated

TAS

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

multicellular organism growth

IEA

1 reference

14 February 2019

Specification of dopaminergic subsets involves interplay of En1 and Pitx3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

adult locomotory behavior

1 reference

14 February 2019

Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid- and hindbrain in a gene dose-dependent manner

hindbrain development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development

cerebellum development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

1 reference

14 February 2019

Specification of dopaminergic subsets involves interplay of En1 and Pitx3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

multicellular organism development

2 references

1 reference

14 February 2019

Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

midbrain-hindbrain boundary development

1 reference

14 February 2019

Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid- and hindbrain in a gene dose-dependent manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

embryonic brain development

1 reference

14 February 2019

Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

1 reference

14 February 2019

Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

embryonic limb morphogenesis

3 references

14 February 2019

Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

14 February 2019

The mouse Engrailed-1 gene and ventral limb patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

14 February 2019

En1 and Wnt7a interact with Dkk1 during limb development in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

Midbrain dopaminergic neurons: control of their cell fate by the engrailed transcription factors

neuron differentiation

3 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09065&geneProductId=UniProtKB:P09065

7 November 2018

Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09065&geneProductId=UniProtKB:P09065

7 November 2018

Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid- and hindbrain in a gene dose-dependent manner

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09065&geneProductId=UniProtKB:P09065

1 reference

14 February 2019

Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

1 reference

14 February 2019

Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

embryonic forelimb morphogenesis

1 reference

14 February 2019

Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

3 references

14 February 2019

Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

14 February 2019

Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

14 February 2019

Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid- and hindbrain in a gene dose-dependent manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

positive regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Protease nexin-1 is expressed at the mouse met-/mesencephalic junction and FGF signaling regulates its promoter activity in primary met-/mesencephalic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

negative regulation of neuron death

IDA

1 reference

14 February 2019

Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons

IBA

neuron differentiation

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

14 February 2019

Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid- and hindbrain in a gene dose-dependent manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

14 February 2019

Midbrain dopaminergic neurons: control of their cell fate by the engrailed transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09065

Homeobox engrailed-type, conserved site

IBA

has part(s)

1 reference

Homeobox domain

1 reference

Homeobox domain engrailed

1 reference

Homeobox, conserved site

1 reference

Homeobox engrailed, C-terminal

1 reference

Homeobox domain, metazoa

1 reference