(Q21979843)

Protein kinase-like domain superfamily

1 reference

PH-like domain superfamily

1 reference

RGS domain superfamily

1 reference

membrane proteins

1 reference

inferred from GOA cell component → membrane

pleckstrin homology domain, protein family

1 reference

Regulator of G protein signalling

1 reference

AGC-kinase, C-terminal domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

protein serine/threonine kinase activity

IEA

2 references

G protein-coupled receptor kinase activity

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

14 February 2019

Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

14 February 2019

Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

14 February 2019

G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

G protein-coupled receptor binding

IDA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

ubiquitin protein ligase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

delta-type opioid receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

kappa-type opioid receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

scaffold protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

basolateral plasma membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

apical plasma membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

regulation of the force of heart contraction

IEA

1 reference

14 February 2019

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

14 February 2019

Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

peptidyl-serine phosphorylation

IMP

1 reference

14 February 2019

GRK2 interacts with and phosphorylates Nedd4 and Nedd4-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

peptidyl-threonine phosphorylation

IDA

1 reference

14 February 2019

GRK2 interacts with and phosphorylates Nedd4 and Nedd4-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

desensitization of G protein-coupled receptor signaling pathway

IEA

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

14 February 2019

Enhanced contractility and decreased beta-adrenergic receptor kinase-1 in mice lacking endogenous norepinephrine and epinephrine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

14 February 2019

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

response to oxidative stress

IGI

protein phosphorylation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

response to organic cyclic compound

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

positive regulation of catecholamine secretion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

follicle-stimulating hormone signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

negative regulation of G protein-coupled receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

positive regulation of vasoconstriction

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

positive regulation of sensory perception of pain

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

positive regulation of excitatory postsynaptic potential

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

positive regulation of muscle cell apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

negative regulation of peptidyl-threonine phosphorylation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

negative regulation of peptidyl-serine phosphorylation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

negative regulation of apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

negative regulation of glucose import

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

positive regulation of fibroblast proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

maintenance of protein location in nucleus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

cellular response to glucose stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

positive regulation of vascular associated smooth muscle cell proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

oligodendrocyte differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

cellular response to epidermal growth factor stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

negative regulation of cellular response to insulin stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

cellular response to chemokine

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

negative regulation of cysteine-type endopeptidase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99MK8

has part(s)

AGC-kinase, C-terminal

1 reference

serine/threonine-protein kinase, active site

1 reference

pleckstrin homology domain

1 reference

protein kinase, ATP binding site

1 reference

RGS domain

1 reference

protein kinase domain

1 reference

inferred by common MeSH mappings on source and on Wikidata

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference