Wikidata

(Q21981065)

English

E1A binding protein p300

mammalian protein found in Mus musculus

  • histone butyryltransferase p300
  • protein lactyltransferas p300
  • histone acetyltransferase p300
  • protein 2-hydroxyisobutyryltransferase p300
  • protein propionyltransferase p300
  • E1A-associated protein p300
  • Ep300
  • histone crotonyltransferase p300
In more languages

Statements

part of
molecular function
protein binding
determination method
IPI
19 references
retrieved
14 February 2019
stated in
p300-dependent acetylation of activating transcription factor 5 enhances C/EBPβ transactivation of C/EBPα during 3T3-L1 differentiation
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expression
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
The orphan nuclear receptor RORalpha restrains adipocyte differentiation through a reduction of C/EBPbeta activity and perilipin gene expression
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
Scleraxis and E47 cooperatively regulate the Sox9-dependent transcription
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
Histone acetyltransferase-dependent chromatin remodeling and the vascular clock
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
The small chromatin-binding protein p8 coordinates the association of anti-proliferative and pro-myogenic proteins at the myogenin promoter
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
BCL11B participates in the activation of IL2 gene expression in CD4+ T lymphocytes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
Regulation of p53 by Mdm2 E3 ligase function is dispensable in embryogenesis and development, but essential in response to DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
Binding and modulation of p53 by p300/CBP coactivators
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
retrieved
14 February 2019
stated in
p85α mediates p53 K370 acetylation by p300 and regulates its promoter-specific transactivity in the cellular UVB response
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IPI
transcription coactivator activity
determination method
ISS
IEA
IMP
ISO
6 references
retrieved
14 February 2019
stated in
Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
ISS
retrieved
14 February 2019
stated in
Regulation of E2A activities by histone acetyltransferases in B lymphocyte development
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
ISO
retrieved
14 February 2019
stated in
MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IEA
cell component
biological process
regulation of transcription, DNA-templated
determination method
IDA
ISS
IEA
ISO
6 references
retrieved
14 February 2019
stated in
Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IEA
retrieved
14 February 2019
stated in
Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IDA
retrieved
14 February 2019
stated in
SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IDA
positive regulation of transcription by RNA polymerase II
determination method
IDA
IGI
ISS
IEA
ISO
8 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
ISO
retrieved
14 February 2019
stated in
Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-kappaB-dependent gene expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IGI
retrieved
14 February 2019
stated in
Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IGI
retrieved
14 February 2019
stated in
RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IGI
retrieved
14 February 2019
stated in
New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IGI
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IEA
retrieved
14 February 2019
stated in
The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells
GOA
curator
UniProt
UniProt protein ID
B2RWS6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:B2RWS6
determination method
IDA

Identifiers

 
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