(Q21981188)

Ankyrin repeat-containing domain superfamily

1 reference

membrane proteins

1 reference

inferred from GOA cell component → membrane

Ankyrin-3, death domain, protein family

1 reference

Ankyrin repeat-containing domain, protein family

1 reference

Death domain, protein family

1 reference

ZU5 domain, protein family

1 reference

Ankyrin repeat, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

2 references

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

protein-macromolecule adaptor activity

IBA

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

transmembrane transporter binding

1 reference

16 September 2017

Ankyrin-3 is a novel binding partner of the voltage-gated potassium channel Kv1.1 implicated in renal magnesium handling

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

cytoskeletal protein binding

IPI

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

structural constituent of cytoskeleton

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

phosphorylation-dependent protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier

paranode region of axon

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

spectrin-associated cytoskeleton

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

1 reference

16 September 2017

Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

neuromuscular junction

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

sarcoplasmic reticulum

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

bicellular tight junction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

basal plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

basolateral plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

lateral plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

5 references

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

16 September 2017

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

16 September 2017

A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

16 September 2017

Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

16 September 2017

Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

Voltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function In Vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory Neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

IDA

postsynaptic membrane

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

negative regulation of delayed rectifier potassium channel activity

IDA

biological process

1 reference

8 April 2019

Ankyrin-3 is a novel binding partner of the voltage-gated potassium channel Kv1.1 implicated in renal magnesium handling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

magnesium ion homeostasis

1 reference

8 April 2019

Ankyrin-3 is a novel binding partner of the voltage-gated potassium channel Kv1.1 implicated in renal magnesium handling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

positive regulation of action potential

1 reference

8 April 2019

A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

1 reference

8 April 2019

Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

cellular response to magnesium ion

1 reference

8 April 2019

Ankyrin-3 is a novel binding partner of the voltage-gated potassium channel Kv1.1 implicated in renal magnesium handling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

1 reference

8 April 2019

Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

1 reference

8 April 2019

Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

neuronal action potential

1 reference

8 April 2019

AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

neuromuscular junction development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

positive regulation of cell communication by electrical coupling

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

positive regulation of protein targeting to membrane

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

positive regulation of cation channel activity

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

positive regulation of homotypic cell-cell adhesion

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

positive regulation of sodium ion transmembrane transporter activity

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

positive regulation of sodium ion transport

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

positive regulation of membrane depolarization during cardiac muscle cell action potential

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

regulation of potassium ion transport

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

cytoskeleton organization

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

positive regulation of gene expression

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

positive regulation of membrane potential

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

plasma membrane organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

Golgi to plasma membrane protein transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

establishment of protein localization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

protein localization to plasma membrane

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

Ankyrin-G is a molecular partner of E-cadherin in epithelial cells and early embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

maintenance of protein location in plasma membrane

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

protein localization to axon

1 reference

16 September 2017

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5E8K5&geneProductId=UniProtKB:G5E8K5

protein localization to axon

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

8 April 2019

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

clustering of voltage-gated sodium channels

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5E8K5

ankyrin repeat-containing domain

has part(s)

1 reference

Death domain

1 reference

ZU5 domain

1 reference

ankyrin repeat

1 reference

Ankyrin-3, death domain

1 reference