(Q21981635)

Neurotransmitter-gated ion-channel transmembrane domain superfamily

1 reference

Nicotinic acetylcholine receptor

1 reference

Neurotransmitter-gated ion-channel transmembrane domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Neurotransmitter-gated ion-channel ligand-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Neurotransmitter-gated ion-channel, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

18 December 2019

1 reference

18 December 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

1 reference

14 February 2019

UBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

extracellular ligand-gated ion channel activity

IPI

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4G9&geneProductId=UniProtKB:Q8R4G9

acetylcholine receptor activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4G9&geneProductId=UniProtKB:Q8R4G9

acetylcholine-gated cation-selective channel activity

serotonin-gated cation-selective channel activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4G9&geneProductId=UniProtKB:Q8R4G9

transmembrane signaling receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

acetylcholine binding

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4G9&geneProductId=UniProtKB:Q8R4G9

protein heterodimerization activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

2 references

14 February 2019

A null mutation for the alpha3 nicotinic acetylcholine (ACh) receptor gene abolishes fast synaptic activity in sympathetic ganglia and reveals that ACh output from developing preganglionic terminals is regulated in an activity-dependent retrograde m

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

14 February 2019

A null mutation for the alpha3 nicotinic acetylcholine (ACh) receptor gene abolishes fast synaptic activity in sympathetic ganglia and reveals that ACh output from developing preganglionic terminals is regulated in an activity-dependent retrograde m

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

integral component of membrane

IDA

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

2 references

postsynaptic membrane

1 reference

14 February 2019

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4G9&geneProductId=UniProtKB:Q8R4G9

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

integral component of plasma membrane

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

acetylcholine-gated channel complex

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

14 February 2019

Postnatal upregulation of alpha4 and alpha3 nicotinic receptor subunits in the brain of alpha7 nicotinic receptor-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

14 February 2019

A null mutation for the alpha3 nicotinic acetylcholine (ACh) receptor gene abolishes fast synaptic activity in sympathetic ganglia and reveals that ACh output from developing preganglionic terminals is regulated in an activity-dependent retrograde m

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

14 February 2019

A null mutation for the alpha3 nicotinic acetylcholine (ACh) receptor gene abolishes fast synaptic activity in sympathetic ganglia and reveals that ACh output from developing preganglionic terminals is regulated in an activity-dependent retrograde m

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

14 February 2019

Dystrophin stabilizes alpha 3- but not alpha 7-containing nicotinic acetylcholine receptor subtypes at the postsynaptic apparatus in the mouse superior cervical ganglion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

regulation of muscle contraction

IDA

biological process

1 reference

14 February 2019

Megacystis, mydriasis, and ion channel defect in mice lacking the alpha3 neuronal nicotinic acetylcholine receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

1 reference

14 February 2019

The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

regulation of membrane potential

1 reference

24 April 2018

Megacystis, mydriasis, and ion channel defect in mice lacking the alpha3 neuronal nicotinic acetylcholine receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4G9&geneProductId=UniProtKB:Q8R4G9

regulation of acetylcholine secretion, neurotransmission

1 reference

14 February 2019

A null mutation for the alpha3 nicotinic acetylcholine (ACh) receptor gene abolishes fast synaptic activity in sympathetic ganglia and reveals that ACh output from developing preganglionic terminals is regulated in an activity-dependent retrograde m

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

synaptic transmission, cholinergic

1 reference

24 April 2018

A null mutation for the alpha3 nicotinic acetylcholine (ACh) receptor gene abolishes fast synaptic activity in sympathetic ganglia and reveals that ACh output from developing preganglionic terminals is regulated in an activity-dependent retrograde m

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4G9&geneProductId=UniProtKB:Q8R4G9

2 references

nervous system development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

regulation of dendrite morphogenesis

1 reference

14 February 2019

Mice lacking specific nicotinic acetylcholine receptor subunits exhibit dramatically altered spontaneous activity patterns and reveal a limited role for retinal waves in forming ON and OFF circuits in the inner retina

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

excitatory postsynaptic potential

1 reference

14 February 2019

A null mutation for the alpha3 nicotinic acetylcholine (ACh) receptor gene abolishes fast synaptic activity in sympathetic ganglia and reveals that ACh output from developing preganglionic terminals is regulated in an activity-dependent retrograde m

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

activation of transmembrane receptor protein tyrosine kinase activity

1 reference

14 February 2019

A null mutation for the alpha3 nicotinic acetylcholine (ACh) receptor gene abolishes fast synaptic activity in sympathetic ganglia and reveals that ACh output from developing preganglionic terminals is regulated in an activity-dependent retrograde m

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4G9&geneProductId=UniProtKB:Q8R4G9

ion transmembrane transport

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4G9&geneProductId=UniProtKB:Q8R4G9

serotonin receptor signaling pathway

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8R4G9&geneProductId=UniProtKB:Q8R4G9

protein heterooligomerization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

acetylcholine receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

response to acetylcholine

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

chemical synaptic transmission

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

synaptic transmission, cholinergic

2 references

14 February 2019

A null mutation for the alpha3 nicotinic acetylcholine (ACh) receptor gene abolishes fast synaptic activity in sympathetic ganglia and reveals that ACh output from developing preganglionic terminals is regulated in an activity-dependent retrograde m

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

neuromuscular synaptic transmission

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

nervous system process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

regulation of synaptic vesicle exocytosis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8R4G9

Neurotransmitter-gated ion-channel ligand-binding domain

has part(s)

1 reference

Neurotransmitter-gated ion-channel transmembrane domain

1 reference

Neurotransmitter-gated ion-channel, conserved site

1 reference