(Q21984216)

Translation initiation factor 2, alpha subunit, middle domain superfamily

1 reference

Translation initiation factor 2, alpha subunit, C-terminal

1 reference

Nucleic acid-binding, OB-fold

1 reference

RNA-binding domain, S1, protein family

1 reference

based on heuristic

inferred from protein domain or family

S1 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

translation initiation factor activity

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

2 references

14 February 2019

Treatment of cells with the angiogenic inhibitor fumagillin results in increased stability of eukaryotic initiation factor 2-associated glycoprotein, p67, and reduced phosphorylation of extracellular signal-regulated kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

Autophosphorylation of heme-regulated eukaryotic initiation factor 2α kinase and the role of the modification in catalysis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

2 references

eukaryotic 48S preinitiation complex

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZWX6&geneProductId=UniProtKB:Q6ZWX6

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

eukaryotic translation initiation factor 2B complex

IBA

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

translation initiation ternary complex

IBA

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZWX6&geneProductId=UniProtKB:Q6ZWX6

3 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZWX6&geneProductId=UniProtKB:Q6ZWX6

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZWX6&geneProductId=UniProtKB:Q6ZWX6

31 January 2018

Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZWX6&geneProductId=UniProtKB:Q6ZWX6

glial limiting end-foot

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZWX6&geneProductId=UniProtKB:Q6ZWX6

eukaryotic translation initiation factor 2 complex

3 references

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

Perk is essential for translational regulation and cell survival during the unfolded protein response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

negative regulation of translational initiation in response to stress

1 reference

14 February 2019

Activation of GCN2 in UV-irradiated cells inhibits translation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

Activation of GCN2 in UV-irradiated cells inhibits translation

cellular response to UV

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

cellular response to amino acid starvation

1 reference

14 February 2019

Regulated translation initiation controls stress-induced gene expression in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZWX6&geneProductId=UniProtKB:Q6ZWX6

response to manganese-induced endoplasmic reticulum stress

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

protein autophosphorylation

1 reference

14 February 2019

Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

regulation of translation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

regulation of translational initiation in response to stress

1 reference

14 February 2019

IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

response to endoplasmic reticulum stress

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

Regulated translation initiation controls stress-induced gene expression in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

cellular response to heat

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZWX6&geneProductId=UniProtKB:Q6ZWX6

positive regulation of type B pancreatic cell apoptotic process

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZWX6&geneProductId=UniProtKB:Q6ZWX6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

translational initiation

1 reference

14 February 2019

negative regulation of guanyl-nucleotide exchange factor activity

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZWX6&geneProductId=UniProtKB:Q6ZWX6

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

AMP Kinase Activation Alters Oxidant-Induced Stress Granule Assembly by Modulating Cell Signaling and Microtubule Organization

stress granule assembly

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

cellular response to oxidative stress

IMP

1 reference

14 February 2019

AMP Kinase Activation Alters Oxidant-Induced Stress Granule Assembly by Modulating Cell Signaling and Microtubule Organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZWX6

1 reference

RNA-binding domain, S1

1 reference