Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q21985111)
Watch
English
Mitogen-activated protein kinase kinase kinase kinase 2
mammalian protein found in Mus musculus
MEK kinase kinase 2
germinal center kinase
MAPK/ERK kinase kinase kinase 2
Map4k2
GCK
rab8-interacting protein
MEKKK 2
RAB8 interacting protein
mitogen-activated protein kinase kinase kinase kinase 2
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61161
part of
mitogen-activated protein (MAP) kinase kinase kinase kinase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61161
Protein kinase-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61161
membrane proteins
1 reference
based on heuristic
inferred from GOA cell component → membrane
Citron homology (CNH) domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase, ATP binding site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61161
encoded by
Map4k2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61161
molecular function
transferase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
nucleotide binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
protein kinase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
mitogen-activated protein kinase kinase kinase binding
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
kinase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
ATP binding
determination method
ISS
IEA
ISO
5 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
protein serine/threonine kinase activity
determination method
IEA
ISO
3 references
retrieved
27 March 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61161&geneProductId=UniProtKB:Q61161
determination method
ISO
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61161&geneProductId=UniProtKB:Q61161
determination method
IEA
retrieved
27 March 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61161&geneProductId=UniProtKB:Q61161
determination method
IEA
MAP kinase kinase kinase kinase activity
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IBA
protein serine/threonine kinase activity
determination method
IBA
IEA
ISO
4 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IBA
cell component
cytoplasm
determination method
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IBA
Golgi apparatus
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
Golgi membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
plasma membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
basolateral plasma membrane
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
biological process
intracellular signal transduction
determination method
ISS
IEA
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
vesicle targeting
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IDA
phosphorylation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
immune system process
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
positive regulation of JNK cascade
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
protein phosphorylation
determination method
ISS
IEA
ISO
4 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
innate immune response
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61161
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IEA
regulation of mitotic cell cycle
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61161&geneProductId=UniProtKB:Q61161
determination method
IBA
stress-activated protein kinase signaling cascade
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IBA
regulation of apoptotic process
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61161&geneProductId=UniProtKB:Q61161
determination method
IBA
signal transduction
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IBA
activation of protein kinase activity
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61161
determination method
IBA
has part(s)
Citron homology (CNH) domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61161
protein kinase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61161
protein kinase, ATP binding site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61161
Identifiers
RefSeq protein ID
NP_001278716
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
26412
NP_033032
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
26412
XP_006531818
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
26412
XP_006531819
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
26412
XP_006531820
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
26412
XP_006531823
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
26412
XP_017173700
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
26412
XP_017173701
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
26412
XP_036017493
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
26412
UniProt protein ID
Q61161
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61161
Ensembl protein ID
ENSMUSP00000025897
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000025897
ENSMUSP00000121375
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000121375
ENSMUSP00000121856
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000121856
ENSMUSP00000114243
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000114243
ENSMUSP00000115741
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000115741
ENSMUSP00000120123
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000120123
ENSMUSP00000158086
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000158086
ENSMUSP00000158007
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000158007
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
