(Q21986018)

Winged helix-like DNA-binding domain superfamily

1 reference

Interferon regulatory factor 1

1 reference

Interferon regulatory factors

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

DNA-binding transcription activator activity, RNA polymerase II-specific

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15314&geneProductId=UniProtKB:P15314

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15314&geneProductId=UniProtKB:P15314

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

5 references

14 February 2019

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

Cell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

DNA-binding transcription factor activity

IPI

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15314&geneProductId=UniProtKB:P15314

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15314&geneProductId=UniProtKB:P15314

24 April 2018

IFN-gamma upregulates expression of the mouse complement C1rA gene in keratinocytes via IFN-regulatory factor-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15314&geneProductId=UniProtKB:P15314

24 April 2018

Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15314&geneProductId=UniProtKB:P15314

DNA-binding transcription factor activity

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

IFN-gamma upregulates expression of the mouse complement C1rA gene in keratinocytes via IFN-regulatory factor-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15314&geneProductId=UniProtKB:P15314

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15314&geneProductId=UniProtKB:P15314

1 January 2018

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15314&geneProductId=UniProtKB:P15314

1 January 2018

Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15314&geneProductId=UniProtKB:P15314

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

regulation of CD8-positive, alpha-beta T cell proliferation

1 reference

14 February 2019

Interferon regulatory factor-1 (IRF-1) shapes both innate and CD8(+) T cell immune responses against West Nile virus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

CD8-positive, alpha-beta T cell differentiation

1 reference

14 February 2019

Overexpression of Bcl-2 differentially restores development of thymus-derived CD4-8+ T cells and intestinal intraepithelial T cells in IFN-regulatory factor-1-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

negative regulation of T-helper 2 cell differentiation

1 reference

14 February 2019

IRF family of transcription factors as regulators of host defense

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

regulation of innate immune response

1 reference

14 February 2019

Interferon regulatory factor-1 (IRF-1) shapes both innate and CD8(+) T cell immune responses against West Nile virus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

negative regulation of regulatory T cell differentiation

1 reference

14 February 2019

IFN regulatory factor-1 negatively regulates CD4+ CD25+ regulatory T cell differentiation by repressing Foxp3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

positive regulation of natural killer cell differentiation

1 reference

14 February 2019

IRF family of transcription factors as regulators of host defense

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

interferon-gamma-mediated signaling pathway

1 reference

14 February 2019

Interferon regulatory factor-1 (IRF-1) shapes both innate and CD8(+) T cell immune responses against West Nile virus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15314&geneProductId=UniProtKB:P15314

immune system process

1 reference

1 January 2018

positive regulation of T-helper 1 cell differentiation

1 reference

14 February 2019

IRF family of transcription factors as regulators of host defense

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

regulation of adaptive immune response

1 reference

14 February 2019

Interferon regulatory factor-1 (IRF-1) shapes both innate and CD8(+) T cell immune responses against West Nile virus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

regulation of MyD88-dependent toll-like receptor signaling pathway

1 reference

14 February 2019

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15314&geneProductId=UniProtKB:P15314

positive regulation of transcription, DNA-templated

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

IFN regulatory factor-1 bypasses IFN-mediated antiviral effects through viperin gene induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

cellular response to mechanical stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

regulation of immune response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

regulation of gene expression

1 reference

14 February 2019

Overexpression of Bcl-2 differentially restores development of thymus-derived CD4-8+ T cells and intestinal intraepithelial T cells in IFN-regulatory factor-1-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

innate immune response

1 reference

14 February 2019

negative regulation of transcription, DNA-templated

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

IFN regulatory factor-1 negatively regulates CD4+ CD25+ regulatory T cell differentiation by repressing Foxp3 expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

positive regulation of type I interferon production

1 reference

14 February 2019

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

positive regulation of transcription by RNA polymerase II

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

IFN-gamma upregulates expression of the mouse complement C1rA gene in keratinocytes via IFN-regulatory factor-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

negative regulation of cell population proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

positive regulation of interferon-beta production

3 references

transcription by RNA polymerase II

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15314&geneProductId=UniProtKB:P15314

defense response to virus

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

I-kappaB kinase/NF-kappaB signaling

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

positive regulation of cell death

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

negative regulation of tyrosine phosphorylation of STAT protein

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

response to growth hormone

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

cellular response to interleukin-1

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

cellular response to tumor necrosis factor

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

cellular response to peptide hormone stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15314

Interferon regulatory factor DNA-binding domain

has part(s)

1 reference

Interferon regulatory factor, conserved site

1 reference