(Q21987108)

English

Parvin, alpha

mammalian protein found in Mus musculus

Parva
actopaxin
alpha-parvin

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

CH domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9EPC1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9EPC1

membrane proteins

1 reference

based on heuristic

inferred from GOA cell component → membrane

Calponin homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein binding

determination method

5 references

8 April 2019

Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Integrin-linked kinase is an adaptor with essential functions during mouse development

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

determination method

4 references

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPC1&geneProductId=UniProtKB:Q9EPC1

determination method

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPC1&geneProductId=UniProtKB:Q9EPC1

determination method

24 April 2018

Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPC1&geneProductId=UniProtKB:Q9EPC1

determination method

24 April 2018

Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPC1&geneProductId=UniProtKB:Q9EPC1

determination method

cadherin binding

determination method

1 reference

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPC1&geneProductId=UniProtKB:Q9EPC1

determination method

determination method

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

determination method

6 references

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPC1&geneProductId=UniProtKB:Q9EPC1

determination method

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPC1&geneProductId=UniProtKB:Q9EPC1

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPC1&geneProductId=UniProtKB:Q9EPC1

determination method

24 April 2018

Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPC1&geneProductId=UniProtKB:Q9EPC1

determination method

24 April 2018

Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPC1&geneProductId=UniProtKB:Q9EPC1

determination method

24 April 2018

Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPC1&geneProductId=UniProtKB:Q9EPC1

determination method

plasma membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

determination method

1 reference

8 April 2019

Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

determination method

1 reference

8 April 2019

Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

protein-containing complex

determination method

1 reference

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

determination method

7 references

8 April 2019

The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

actin cytoskeleton

determination method

biological process

actin cytoskeleton reorganization

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPC1&geneProductId=UniProtKB:Q9EPC1

determination method

smooth muscle cell chemotaxis

determination method

1 reference

8 April 2019

Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

heterotypic cell-cell adhesion

determination method

1 reference

8 April 2019

Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

sprouting angiogenesis

determination method

1 reference

8 April 2019

Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

outflow tract septum morphogenesis

determination method

1 reference

8 April 2019

Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

establishment or maintenance of cell polarity

determination method

1 reference

24 April 2018

Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9EPC1&geneProductId=UniProtKB:Q9EPC1

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

actin-mediated cell contraction

determination method

1 reference

8 April 2019

Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

determination method

3 references

cell projection organization

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

regulation of cell shape

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

actin cytoskeleton organization

determination method

1 reference

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

protein heterooligomerization

determination method

1 reference

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

cell projection assembly

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

substrate adhesion-dependent cell spreading

determination method

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

14 February 2019

Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

cilium assembly

determination method

3 references

substrate adhesion-dependent cell spreading

determination method

4 references

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

cilium assembly

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9EPC1

determination method

Calponin homology domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9EPC1

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000033030

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000033030

ENSMUSP00000102254

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000102254

ENSMUSP00000102251

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000102251

ENSMUSP00000118587

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000118587

Sitelinks

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