(Q21987765)

Immunoglobulin-like fold

1 reference

Nuclear factor of activated T cells (NFAT)

1 reference

Rel homology domain (RHD), DNA-binding domain superfamily

1 reference

Immunoglobulin E-set

1 reference

IPT domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Rel homology dimerisation domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Rel homology domain (RHD), DNA-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

2 references

sequence-specific DNA binding

transcription factor binding

1 reference

21 June 2018

A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

1 reference

21 June 2018

A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

RNA polymerase II cis-regulatory region sequence-specific DNA binding

5 references

21 June 2018

NFATc2-mediated repression of cyclin-dependent kinase 4 expression

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Nuclear factor of activated T cells (NFAT) is involved in the depolarization-induced activation of growth hormone-releasing hormone gene transcription in vitro

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Identification and characterization of a novel nuclear factor of activated T-cells-1 isoform expressed in mouse brain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Sequential involvement of NFAT and Egr transcription factors in FasL regulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

DNA-binding transcription repressor activity, RNA polymerase II-specific

5 references

14 February 2019

Lysine 313 of T-box is crucial for modulation of protein stability, DNA binding, and threonine phosphorylation of T-bet

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

NFAT Binding and Regulation of T Cell Activation by the Cytoplasmic Scaffolding Homer Proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

The Histone Acetyltransferase Gcn5 Positively Regulates T Cell Activation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

An innate immunity signaling process suppresses macrophage ABCA1 expression through IRAK-1-mediated downregulation of retinoic acid receptor alpha and NFATc2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Human VRK2 (vaccinia-related kinase 2) modulates tumor cell invasion by hyperactivation of NFAT1 and expression of cyclooxygenase-2

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

DNA-binding transcription factor activity, RNA polymerase II-specific

IPI

1 reference

14 February 2019

Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

transcription cis-regulatory region binding

1 reference

14 February 2019

Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

RNA polymerase II cis-regulatory region sequence-specific DNA binding

5 references

14 February 2019

NFATc2-mediated repression of cyclin-dependent kinase 4 expression

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Sequential involvement of NFAT and Egr transcription factors in FasL regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Nuclear factor of activated T cells (NFAT) is involved in the depolarization-induced activation of growth hormone-releasing hormone gene transcription in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

DNA-binding transcription factor activity

IBA

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Nuclear factor of activated T cells (NFAT) is involved in the depolarization-induced activation of growth hormone-releasing hormone gene transcription in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

8 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Defective T cell development and function in calcineurin A beta -deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Nuclear factor of activated T cells (NFAT) is involved in the depolarization-induced activation of growth hormone-releasing hormone gene transcription in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Dynamic response diversity of NFAT isoforms in individual living cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

transcription regulator complex

1 reference

21 June 2018

Mina, an Il4 repressor, controls T helper type 2 bias

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

3 references

11 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

An innate immunity signaling process suppresses macrophage ABCA1 expression through IRAK-1-mediated downregulation of retinoic acid receptor alpha and NFATc2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Impairment of endothelial-mesenchymal transformation during atrioventricular cushion formation in Tmem100 null embryos

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Calcium/NFAT signalling promotes early nephrogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Nuclear factor of activated T cells (NFAT) is involved in the depolarization-induced activation of growth hormone-releasing hormone gene transcription in vitro

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Dynamic response diversity of NFAT isoforms in individual living cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

5 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Normal function of the transcription factor NFAT1 in wasted mice. Chromosome localization of NFAT1 gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

ribonucleoprotein complex

1 reference

14 February 2019

Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

12 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

An innate immunity signaling process suppresses macrophage ABCA1 expression through IRAK-1-mediated downregulation of retinoic acid receptor alpha and NFATc2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Calcium/NFAT signalling promotes early nephrogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Nuclear factor of activated T cells (NFAT) is involved in the depolarization-induced activation of growth hormone-releasing hormone gene transcription in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Dynamic response diversity of NFAT isoforms in individual living cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Impairment of endothelial-mesenchymal transformation during atrioventricular cushion formation in Tmem100 null embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Normal function of the transcription factor NFAT1 in wasted mice. Chromosome localization of NFAT1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

regulation of transcription, DNA-templated

IBA

biological process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

1 reference

21 June 2018

Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

calcineurin-NFAT signaling cascade

1 reference

21 June 2018

Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

negative regulation of transcription by RNA polymerase II

IGI

1 reference

14 February 2019

NFATc2-mediated repression of cyclin-dependent kinase 4 expression

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis

myotube cell development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

transcription, DNA-templated

IMP

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

positive regulation of myoblast fusion

IEA

1 reference

14 February 2019

IL-4 acts as a myoblast recruitment factor during mammalian muscle growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

positive regulation of gene expression

IMP

1 reference

14 February 2019

An innate immunity signaling process suppresses macrophage ABCA1 expression through IRAK-1-mediated downregulation of retinoic acid receptor alpha and NFATc2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

3 references

positive regulation of transcription by RNA polymerase II

7 references

21 June 2018

A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Nuclear factor of activated T cells (NFAT) is involved in the depolarization-induced activation of growth hormone-releasing hormone gene transcription in vitro

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Identification and characterization of a novel nuclear factor of activated T-cells-1 isoform expressed in mouse brain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

21 June 2018

Sequential involvement of NFAT and Egr transcription factors in FasL regulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

transcription by RNA polymerase II

1 reference

21 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

negative regulation of vascular associated smooth muscle cell differentiation

IEA

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60591&geneProductId=UniProtKB:Q60591

positive regulation of transcription by RNA polymerase II

IEA

6 references

14 February 2019

A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Sequential involvement of NFAT and Egr transcription factors in FasL regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Nuclear factor of activated T cells (NFAT) is involved in the depolarization-induced activation of growth hormone-releasing hormone gene transcription in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60591

Rel homology dimerisation domain

IBA

has part(s)

1 reference

IPT domain

1 reference

Rel homology domain (RHD), DNA-binding domain

1 reference