(Q21989701)

English

Vav 3 oncogene

mammalian protein found in Mus musculus

VAV-3
Vav3
guanine nucleotide exchange factor VAV3

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

SH3-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

CH domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

SH2 domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

Dbl homology (DH) domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

PH-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

smooth muscle protein/calponin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

pleckstrin homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

VAV3 protein, second SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Vav, PH domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Calmodulin-regulated spectrin-associated protein, CH domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Calponin homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

VAV3, SH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Dbl homology (DH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Guanine-nucleotide dissociation stimulator, CDC24, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

guanyl-nucleotide exchange factor activity

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

14 February 2019

Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

protein binding

determination method

1 reference

14 February 2019

Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

epidermal growth factor receptor binding

determination method

1 reference

14 February 2019

Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

metal ion binding

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

plasma membrane

determination method

1 reference

14 February 2019

Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

determination method

1 reference

14 February 2019

Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

biological process

positive regulation of phosphatidylinositol 3-kinase activity

determination method

1 reference

14 February 2019

Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

regulation of Rho protein signal transduction

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

neutrophil chemotaxis

determination method

1 reference

14 February 2019

P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responses

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

regulation of cell size

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

positive regulation of cell adhesion

determination method

1 reference

14 February 2019

Vav GEFs are required for beta2 integrin-dependent functions of neutrophils

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

intracellular signal transduction

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

cell projection assembly

determination method

1 reference

14 February 2019

Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

integrin-mediated signaling pathway

determination method

1 reference

14 February 2019

Vav GEFs are required for beta2 integrin-dependent functions of neutrophils

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

determination method

1 reference

14 February 2019

Vav GEFs are required for beta2 integrin-dependent functions of neutrophils

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

determination method

1 reference

14 February 2019

Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

lamellipodium assembly

determination method

1 reference

14 February 2019

Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

regulation of GTPase activity

determination method

small GTPase mediated signal transduction

determination method

1 reference

14 February 2019

Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0C8

determination method

Calmodulin-regulated spectrin-associated protein, CH domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

Calponin homology domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

Dbl homology (DH) domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

pleckstrin homology domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

Guanine-nucleotide dissociation stimulator, CDC24, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

protein kinase C-like, phorbol ester/diacylglycerol-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

VAV3 protein, second SH3 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

VAV3, SH2 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9R0C8

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000036270

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000036270

ENSMUSP00000102186

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000102186

Sitelinks

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Multilingual sites(0 entries)

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