(Q21990088)

http://www.ebi.ac.uk/interpro/protein/Q60714

AMP-dependent synthetase/ligase family

1 reference

based on heuristic

inferred from protein domain or family

AMP-binding, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

protein homodimerization activity

1 reference

14 February 2019

Impaired NF-kappa B activation and increased production of tumor necrosis factor alpha in transgenic mice expressing keratin K10 in the basal layer of the epidermis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

fatty acid transmembrane transporter activity

5 references

24 April 2018

Functional domains of the fatty acid transport proteins: studies using protein chimeras

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

A family of fatty acid transporters conserved from mycobacterium to man

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

Oligomerization of the murine fatty acid transport protein 1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

1 reference

14 February 2019

EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

long-chain fatty acid-CoA ligase activity

IPI

3 references

24 April 2018

X-linked adrenoleukodystrophy: role of very long-chain acyl-CoA synthetases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

very long-chain fatty acid-CoA ligase activity

3 references

14 February 2019

The fatty acid transport protein (FATP1) is a very long chain acyl-CoA synthetase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

Functional domains of the fatty acid transport proteins: studies using protein chimeras

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

long-chain fatty acid-CoA ligase activity

4 references

14 February 2019

X-linked adrenoleukodystrophy: role of very long-chain acyl-CoA synthetases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

long-chain fatty acid transporter activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

fatty acid transmembrane transporter activity

6 references

14 February 2019

Functional domains of the fatty acid transport proteins: studies using protein chimeras

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

A family of fatty acid transporters conserved from mycobacterium to man

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

Oligomerization of the murine fatty acid transport protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

integral component of membrane

FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts

2 references

endoplasmic reticulum

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

1 reference

14 February 2019

X-linked adrenoleukodystrophy: role of very long-chain acyl-CoA synthetases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

7 references

24 April 2018

X-linked adrenoleukodystrophy: role of very long-chain acyl-CoA synthetases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

Fatty acid transport protein 1 is required for nonshivering thermogenesis in brown adipose tissue

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

mitochondrial inner membrane

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

integral component of plasma membrane

ISO

1 reference

14 February 2019

Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

intracellular membrane-bounded organelle

ISO

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

3 references

8 references

14 February 2019

X-linked adrenoleukodystrophy: role of very long-chain acyl-CoA synthetases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

Fatty acid transport protein 1 is required for nonshivering thermogenesis in brown adipose tissue

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

medium-chain fatty acid transport

1 reference

24 April 2018

Functional domains of the fatty acid transport proteins: studies using protein chimeras

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

3 references

14 February 2019

Fatty acid transport protein 1 is required for nonshivering thermogenesis in brown adipose tissue

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

A family of fatty acid transporters conserved from mycobacterium to man

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

Oligomerization of the murine fatty acid transport protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

adiponectin-activated signaling pathway

1 reference

24 April 2018

Activation of AMP-activated protein kinase signaling pathway by adiponectin and insulin in mouse adipocytes: requirement of acyl-CoA synthetases FATP1 and Acsl1 and association with an elevation in AMP/ATP ratio

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

fatty acid metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

positive regulation of protein serine/threonine kinase activity

2 references

24 April 2018

FATP1 mediates fatty acid-induced activation of AMPK in 3T3-L1 adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

Activation of AMP-activated protein kinase signaling pathway by adiponectin and insulin in mouse adipocytes: requirement of acyl-CoA synthetases FATP1 and Acsl1 and association with an elevation in AMP/ATP ratio

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

1 reference

24 April 2018

Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

positive regulation of heat generation

1 reference

24 April 2018

Fatty acid transport protein 1 is required for nonshivering thermogenesis in brown adipose tissue

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

1 reference

24 April 2018

Fatty acid transport protein 1 is required for nonshivering thermogenesis in brown adipose tissue

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

long-chain fatty acid metabolic process

1 reference

14 February 2019

X-linked adrenoleukodystrophy: role of very long-chain acyl-CoA synthetases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

long-chain fatty acid transport

TAS

1 reference

14 February 2019

FATP1 is an insulin-sensitive fatty acid transporter involved in diet-induced obesity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

positive regulation of triglyceride biosynthetic process

1 reference

14 February 2019

FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

long-chain fatty acid import into cell

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

24 April 2018

Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60714&geneProductId=UniProtKB:Q60714

phosphatidylethanolamine biosynthetic process

3 references

phosphatidic acid biosynthetic process

3 references

phosphatidylglycerol biosynthetic process

3 references

phosphatidylcholine biosynthetic process

3 references

phosphatidylserine biosynthetic process

3 references

phosphatidylinositol biosynthetic process

3 references

cardiolipin biosynthetic process

3 references

adiponectin-activated signaling pathway

long-chain fatty acid import into cell

2 references

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

negative regulation of phospholipid biosynthetic process

3 references

positive regulation of protein serine/threonine kinase activity

3 references

14 February 2019

FATP1 mediates fatty acid-induced activation of AMPK in 3T3-L1 adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

Activation of AMP-activated protein kinase signaling pathway by adiponectin and insulin in mouse adipocytes: requirement of acyl-CoA synthetases FATP1 and Acsl1 and association with an elevation in AMP/ATP ratio

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60714

AMP-dependent synthetase/ligase

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q60714

AMP-binding, conserved site

1 reference

stated in

InterPro Release 71.0